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Protein Overview: him-10

General Information:
Name(s) found: him-10 / CE01367 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00001869 locus:him-10 Kinetochore protein Nuf2 homolog status:Confirmed UniProt:Q21952 protein_id:CCD73315.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 490 amino acids

    Gene Ontology:
    Cellular Component: kinetochore [IDALink to PubMed article]
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    mitotic spindle organization [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    kinetochore organization [IMPLink to PubMed article]
    meiotic chromosome segregation [IMPLink to PubMed article]
    attachment of spindle microtubules to kinetochore [IMPLink to PubMed article]
    mitotic sister chromatid segregation [IMPLink to PubMed article]
    Molecular Function: structural molecule activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNVVLIVYD PRMISKYLGQ KLHMGLVADD IIKPTAEIAQ QIFANFVRLV LNVSESSLTT  60
   61 LPLSANCDYD PELHKKSIPI IILFQCMKAF IKDNSGNKLD LTMCDLVTPA KHEHRFRKLT 120
  121 SFLVDFLKLH ELATPAFNEI SEEFSDRKFE MEKIREELLE AEKKKNDLLA KQSIRKRHEH 180
  181 ELINEQSNAK AELKNVVNEY TETRQINEEL DKQKEEAILH IQALEKEMLT GKKTIEHLNE 240
  241 EVLTSPEQLK QEMEERKRHI EELRDCLESS KKGLQAKLEA REICINSEKN VPVIIEKIHQ 300
  301 WTEVREVIID LIDVESENLR KLKEMEEQLD FMMKEMETAQ KRLVEQSETH EQLRIEHTQK 360
  361 SEERQRRIEE ITEQIANLKT SQPDVSQEIA KKKQELLALK NAHSETISQI TNSCQDAVAK 420
  421 FAKLNAMFKE TQKVAFEKNT AAAREMERLK SSLTGRLLSD YTFGSSTIDA GENTENCDPQ 480
  481 PNDSSFSVFK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered No Comments Cheeseman, I.M., et al. (2004)
    View Run knl-1 No Comments Cheeseman, I.M., et al. (2004)
    View Run None Entered No Comments Cheeseman, I.M., et al. (2004)
    View Run None Entered No Comments Cheeseman, I.M., et al. (2004)
    View Run gi|7499968 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..490] PSI-BLAST 28.221849 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle