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Protein Overview: CE01225

General Information:
Name(s) found: CE01225 [WormBase]
Description(s) found:
Found 24 descriptions.
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  • WBGene00017166 locus:aldo-2 Fructose-bisphosphate aldolase 2 status:Confirmed UniProt:P46563 protein_id:CCD65997.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 366 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    glycolysis [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    Molecular Function: fructose-bisphosphate aldolase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATVGGAFKD SLTQAQKDEL HQIALKIVQD GKGILAADES TGTIGKRLDA INLENNETNR  60
   61 QKYRQLLFTT PNLNQHISGV ILYEETFHQS TDKGEKFTDL LIKQGIVPGI KLDLGVVPLA 120
  121 GTIGEGTTQG LDKLAERAAA FKKGGCGFAK WRCVLNIGTH TPSHLGMLEN ANVLARYASI 180
  181 CQANGLVPIV EPEVLCDGEH DLARAQKVTE QVLAFVYKAL ADHHVYLEGT LLKPNMVTPG 240
  241 QSSASKASHE AIGLATVTAL RRGVPAAVPG ITFLSGGQSE LDATANLNAI NSVQLGKPWK 300
  301 LTFSYGRALQ ASVLKAWGGK DENIAAAQKT LLHRSKANGD ASLGKYAGED AAGAAAESLF 360
  361 VAKHSY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..366] PSI-BLAST 174.0 ACTIVITY AND SPECIFICITY OF HUMAN ALDOLASES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.60134261588676 bayes_pls_golite062009
  • actin binding
    		•  3.10644195256671 bayes_pls_golite062009
  • fructose-bisphosphate aldolase activity
    		•  2.73042975776531 bayes_pls_golite062009
  • catalytic activity
    		•  2.67031204377352 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.52695263878709 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.40685906151662 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.22908679805492 bayes_pls_golite062009
  • transaldolase activity
    		•  2.1279240183212 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.79169585096618 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.73829975328154 bayes_pls_golite062009
  • fructose binding
    		•  1.42916270771409 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.33969084344225 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.28309551705078 bayes_pls_golite062009
  • binding
    		•  1.1388634428163 bayes_pls_golite062009
  • tubulin binding
    		•  1.11163894855817 bayes_pls_golite062009
  • lyase activity
    		•  0.740424046054758 bayes_pls_golite062009
  • porphobilinogen synthase activity
    		•  0.658378297259497 bayes_pls_golite062009
  • signal transducer activity
    		•  0.512195049920148 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.512195049920148 bayes_pls_golite062009
  • aldehyde-lyase activity
    		•  0.351872954170322 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  0.149175795541329 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0619443932677899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle