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Protein Overview: eat-4

General Information:
Name(s) found: eat-4 / CE01109 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00001135 locus:eat-4 Probable vesicular glutamate transporter eat-4 status:Confirmed UniProt:P34644 protein_id:CAA80150.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 576 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: regulation of pharyngeal pumping [IGILink to PubMed article][IMPLink to PubMed article]
    glycerol-3-phosphate transport [IEALink to PubMed article]
    phosphate transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: phosphate transmembrane transporter activity [IEALink to PubMed article]
    glycerol-3-phosphate transmembrane transporter activity [IEALink to PubMed article]
    transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSWNEAWDR GKQMVGEPLA KMTAAAASAT GAAPPQQMQE EGNENPMQMH SNKVLQVMEQ  60
   61 TWIGKCRKRW LLAILANMGF MISFGIRCNF GAAKTHMYKN YTDPYGKVHM HEFNWTIDEL 120
  121 SVMESSYFYG YLVTQIPAGF LAAKFPPNKL FGFGIGVGAF LNILLPYGFK VKSDYLVAFI 180
  181 QITQGLVQGV CYPAMHGVWR YWAPPMERSK LATTAFTGSY AGAVLGLPLS AFLVSYVSWA 240
  241 APFYLYGVCG VIWAILWFCV TFEKPAFHPT ISQEEKIFIE DAIGHVSNTH PTIRSIPWKA 300
  301 IVTSKPVWAI IVANFARSWT FYLLLQNQLT YMKEALGMKI ADSGLLAAIP HLVMGCVVLM 360
  361 GGQLADYLRS NKILSTTAVR KIFNCGGFGG EAAFMLIVAY TTSDTTAIMA LIAAVGMSGF 420
  421 AISGFNVNHL DIAPRYAAIL MGFSNGIGTL AGLTCPFVTE AFTAHSKHGW TSVFLLASLI 480
  481 HFTGVTFYAV YASGELQEWA EPKEEEEWSN KELVNKTGIN GTGYGAAETT FTQLPAGVDS 540
  541 SYQAQAAPAP GTNPFASAWD EHGSSGVVEN PHYQQW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..576] PSI-BLAST 49.69897 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.6188895673796 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.6188895673796 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.78662033436109 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.26757615356623 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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