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Protein Overview: CE01031

General Information:
Name(s) found: CE01031 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00010809 Lipoyl synthase, mitochondrial status:Confirmed UniProt:Q21452 protein_id:CAA86516.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 354 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    lipoate biosynthetic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    lipoate synthase activity [IEALink to PubMed article]
    iron-sulfur cluster binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLARVWVRGL AATKKKPQVL VKDGPSLQDF ISSASVAEAV EKYEGKLKLE KGDRRLRLPP  60
   61 WLKKEKILPS ENENVSRLKK QLKHLKLATV CQEARCPNLG ECWGGSDDSL ATATIMLMGD 120
  121 TCTRGCKFCS VKTARAPPPL DPMEPENTST AVASWGVEYI VLTSVDRDDL PDGGADHLRK 180
  181 TVQLMKLKKP ELLIECLLPD FAGDKISVEK MATSGLDVYA HNIETVERLT PWVRDPRAKY 240
  241 RQSLDALRYA KEVSPKLITK TSIMLGLGEA EDEIKQCLAD LRASNVDVVT FGQYMQPTKR 300
  301 HLLVKEWVTP EKFDQWAEYS KKLGFLYVAS GPLVRSSYKA GEFYLKNVLR NRQN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..52] MSA 2.558996 View MSA. No confident structure predictions are available.
    2 View Details [53..354] PSI-BLAST 48.69897 The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • sulfurtransferase activity
    		•  2.16438226990481 bayes_pls_golite062009
  • biotin synthase activity
    		•  2.08611410724267 bayes_pls_golite062009
  • coproporphyrinogen oxidase activity
    		•  1.98937742831419 bayes_pls_golite062009
  • radical SAM enzyme activity
    		•  1.93582371651697 bayes_pls_golite062009
  • catalytic activity
    		•  1.48331922124015 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
    		•  1.37188743230327 bayes_pls_golite062009
  • transferase activity, transferring sulfur-containing groups
    		•  1.13381681474815 bayes_pls_golite062009
  • binding
    		•  0.998331252589966 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.593156857804038 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.48341859452689 bayes_pls_golite062009
  • protein binding
    		•  0.274298596808905 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle