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Protein Overview: pdi-1

General Information:
Name(s) found: pdi-1 / CE00897 [WormBase]
Description(s) found:
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  • WBGene00003962 locus:pdi-1 Protein disulfide-isomerase 1 status:Confirmed UniProt:Q17967 protein_id:CAA85491.1 [WormBase]
  • pir||S71863 protein disulfide-isomerase (EC 5.3.4.1) isoform I precursor - Caenorhabditis elegans [NCBI NR]
  • gi|3874294|emb|CAA85491.1| C. elegans protein C14B1.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|33112404|sp|Q17967.1|PDI1_CAEEL RecName: Full=Protein disulfide-isomerase 1; Short=PDI 1; AltName: Full=Prolyl 4-hydroxylase subunit beta-1; Flags: Precursor [NCBI NR]
  • gi|2262219|gb|AAB94647.1| protein disulphide isomerase isoform I [Caenorhabditis elegans] [NCBI NR]
  • gi|17554386|ref|NP_497746.1| Protein Disulfide Isomerase family member (pdi-1) [Caenorhabditis elegans] [NCBI NR]
  • Protein disulfide-isomerase 1 OS=Caenorhabditis elegans GN=pdi-1 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE00897 WBGene00003962 locus:pdi-1 protein disulfide isomerase status:Confirmed SW:Q17967 protein_id:CAA85491.1 [wormpep150.fasta]
  • 00897 WBGene00003962 locus:pdi-1 protein disulfide isomerase status:Confirmed SW:Q17967 protein_id:CAA85491.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • protein disulfide isomerase (53.4 kD) (pdi-1) [Caenorhabditis elegans]gi|3874294|emb|CAA85491.1| Hypothetical protein C14B1.1 [Caenorhabditis elegans]gi|2262219|gb|AAB94647.1| protein disulphide isomerase isoform I [Caenorhabditis elegans]gi|7437390|pi [nrdb_11152004_Chlamydomonas]
  • locus:pdi-1 protein disulfide isomerase status:Confirmed SW:Q17967 protein_id:CAA85491.1 [wormpep115.fasta.reversed]
  • CE00897 locus:pdi-1 protein disulfide isomerase status:Confirmed TR:Q17967 protein_id:CAA85491.1 [wormpep80.hongbin]
  • CE00897 WBGene00003962 locus:pdi-1 protein disulfide isomerase status:Confirmed UniProt:Q17967 protein_id:CAA85491.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE00897 WBGene00003962 locus:pdi-1 protein disulfide isomerase status:Confirmed UniProt:Q17967 protein_id:CAA85491.1| [wormORF-contam.fasta]
  • Hypothetical protein C14B1.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Protein disulfide-isomerase 1 precursor (PDI 1) (Prolyl 4-hydroxylase beta 1 subunit) [nr-271106-contam.fasta]
  • protein disulphide isomerase isoform I [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Protein Disulfide Isomerase family member (pdi-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE00897 WBGene00003962 locus:pdi-1 status:Confirmed UniProt:Q17967 protein_id:CAA85491.1 Protein disulfide-isomerase 1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 485 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IEALink to PubMed article]
    Biological Process: glycerol ether metabolic process [IEALink to PubMed article]
    cell redox homeostasis [IEALink to PubMed article]
    Molecular Function: protein-glutamine gamma-glutamyltransferase activity [IDALink to PubMed article]
    protein disulfide isomerase activity [IDALink to PubMed articleLink to PubMed article]
    protein disulfide oxidoreductase activity [IEALink to PubMed article]
    electron carrier activity [IEALink to PubMed article]
    isomerase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSVSFIFL LVASIGAVVA DSENVLVLTE SNFEETINGN EFVLVKFYAP WCVHCKSLAP  60
   61 KYDEAADLLK EEGSDIKLAK VDATENQALA SKFEVRGYPT ILYFKSGKPT KYTGGRATAQ 120
  121 IVDWVKKKSG PTVTTVESVE QLEELKGKTR VVVLGYFKDA KSDAATIYNE VADSVDDAFF 180
  181 AVAGSAEVAA AASLNEDGVA LIRTDGDDSE TSTIAEAEIT NTIALKQWLH AYKLSAVTEF 240
  241 THESAQEIVG GDLKKFHFLI IRKSDSSFDE TIAKFTEVAK KFRAKIVFVL LDVDVEENAR 300
  301 ILEFLGVDAK NTPANRIVSL ADQVEKFKPQ EGEDFEAFTN SYLEGKSAQD LKAQDLPEDW 360
  361 NALPVKVLVA SNFNEIALDE TKTVFVKFYA PWCGHCKQLV PVWDELAEKY ESNPNVVIAK 420
  421 LDATLNELAD VKVNSFPTLK LWPAGSSTPV DYDGDRNLEK FEEFVNKYAG SASESETASQ 480
  481 DHEEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..485] PSI-BLAST 63.39794 Crystal Structure of Yeast Protein Disulfide Isomerase


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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