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Protein Overview: CE00187

General Information:
Name(s) found: CE00187 [WormBase]
Description(s) found:
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  • WBGene00010035 Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1 status:Partially_confirmed UniProt:P34439 protein_id:CAA80153.1 [WormBase]
  • pir||S40743 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) short chain-specific form homolog - Caenorhabditis elegans [NCBI NR]
  • gi|462252|sp|P34439.1|HCDH1_CAEEL RecName: Full=Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1 [NCBI NR]
  • gi|3877485|emb|CAA80153.1| C. elegans protein F54C8.1, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17553560|ref|NP_499075.1| hypothetical protein F54C8.1 [Caenorhabditis elegans] [NCBI NR]
  • Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1 OS=Caenorhabditis elegans GN=F54C8.1 PE=1 SV=1 [Swiss-Prot]
  • (P34439) Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1 (EC 1.1.1.35) [Swiss-Prot]
  • [wormpep67.fasta]
  • CE00187 WBGene00010035 3-hydroxyacyl-CoA dehydrogenase status:Partially_confirmed SW:P34439 protein_id:CAA80153.1 [wormpep150.fasta]
  • 00187 WBGene00010035 3-hydroxyacyl-CoA dehydrogenase status:Partially_confirmed SW:P34439 protein_id:CAA80153.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • short dehydrogenase (3K531) [Caenorhabditis elegans]gi|3877485|emb|CAA80153.1| Hypothetical protein F54C8.1 [Caenorhabditis elegans]gi|482112|pir||S40743 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) short chain-specific form homolog - Caenorhabditis el [nrdb_11152004_Chlamydomonas]
  • 3-hydroxyacyl-CoA dehydrogenase status:Partially_confirmed SW:P34439 protein_id:CAA80153.1 [wormpep115.fasta.reversed]
  • CE00187 3-hydroxyacyl-CoA dehydrogenase status:Predicted SW:P34439 protein_id:CAA80153.1 [wormpep80.hongbin]
  • CE00187 WBGene00010035 3-hydroxyacyl-CoA dehydrogenase status:Partially_confirmed UniProt:P34439 protein_id:CAA80153.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE00187 WBGene00010035 3-hydroxyacyl-CoA dehydrogenase status:Partially_confirmed UniProt:P34439 protein_id:CAA80153.1| [wormORF-contam.fasta]
  • Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1 [nr-271106-contam.fasta]
  • F54C8.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F54C8.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE00187 WBGene00010035 status:Partially_confirmed UniProt:P34439 protein_id:CAA80153.1 Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 298 amino acids

    Gene Ontology:
    Cellular Component: fatty acid beta-oxidation multienzyme complex [IEALink to PubMed article]
    Biological Process: fatty acid beta-oxidation [IEALink to PubMed article]
    fatty acid metabolic process [IEALink to PubMed article]
    Molecular Function: oxidoreductase activity [IEALink to PubMed article]
    3-hydroxyacyl-CoA dehydrogenase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyryl-CoA epimerase activity [IEALink to PubMed article]
    enoyl-CoA hydratase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTAKCAMQN IRNVAIVGSG QMGSGIAQVT ASSGFNVMLA DVNKKALDRA MKAISQSVTH  60
   61 LSKKQKGTDK EKSDFVTLTM SRIKTCNNVS TAVADADLII EAAIENIDLK RGIFAQIEQS 120
  121 CKKDSILTTN TSSFLLEDVA KGLQDKTRFG GLHFFNPVPV MKLLEVIRSD DTSDETYATL 180
  181 IKFGTAVGKT TVACKDSPGF IVNRLLIPYF FEAARMYERG DASMTDIDEA MKLGAGHPMG 240
  241 PFELADYIGL DTVKFVMDGW AAKYPEVQLF EASPLVDKLV AEGKLGRKTG DGFYSYKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..298] PSI-BLAST 61.69897 Short chain L-3-hydroxyacyl CoA dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  3.32932637997329 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.05128385305465 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.96484346513217 bayes_pls_golite062009
  • catalytic activity
    		•  1.83291384546132 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  1.53235113426441 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  1.25489401408719 bayes_pls_golite062009
  • binding
    		•  1.10054369202721 bayes_pls_golite062009
  • transporter activity
    		•  0.793769336118517 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.788034697021177 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  0.715028113460127 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.635891484075352 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.530688665000667 bayes_pls_golite062009
  • phosphogluconate dehydrogenase (decarboxylating) activity
    		•  0.44449320501876 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  0.439912268968251 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.300373102236296 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.239024094835991 bayes_pls_golite062009
  • protein binding
    		•  0.215925602689574 bayes_pls_golite062009
  • signal transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.201915860594054 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.165260811069909 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0257250793986203 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle