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Protein Overview: SPCP31B10.05

General Information:
Name(s) found: SPCP31B10.05 [Sanger Pombe]
Description(s) found:
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  • pir||T41695 hypothetical protein SPCP31B10.05 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74625832|sp|Q9USG9.1|TYDP1_SCHPO RecName: Full=Probable tyrosyl-DNA phosphodiesterase; Short=Tyr-DNA phosphodiesterase [NCBI NR]
  • gi|6066756|emb|CAB58371.1| tyrosyl-DNA phosphodiesterase Tdp1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19075361|ref|NP_587861.1| tyrosyl-DNA phosphodiesterase (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • tyrosyl-DNA phosphodiesterase [Sanger Pombe]
  • Probable tyrosyl-DNA phosphodiesterase OS=Schizosaccharomyces pombe GN=SPCP31B10.05 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE TYROSYL-DNA PHOSPHODIESTERASE, INVOLVED IN DNA REPAIR; SIMILAR TO S. CEREVISIAE TDP1: Q9USG9; [pompepVF.fasta]
  • PUTATIVE TYROSYL-DNA PHOSPHODIESTERASE, INVOLVED IN DNA REPAIR; BY SIMILARITY TO YEAST TDP1: Q9USG9; [pompepV13]
  • Hypothetical protein [pompep4896]
  • |||putative tyrosyl-DNA phosphodiesterase [pompepnew.fasta]
  • SPCP31B10.05 protein [4896.FASTAC]
  • |||tyrosyl-DNA phosphodiesterase (predicted)|Schizosaccharomyces pombe|chr 3|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|6066756|emb|CAB58371.1| SPCP31B10.05 [Schizosaccharomyces pombe]gi|7492012|pir||T41695 hypothetical protein SPCP31B10.05 - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||tyrosyl-DNA phosphodiesterase |Schizosaccharomyces pombe|chr 3|||Manual [pompep2242005.fasta]
  • (Q9USG9) Hypothetical protein [pompep4896_normal_reversed]
  • |tdp1||tyrosyl-DNA phosphodiesterase Tdp1|Schizosaccharomyces pombe|chr 3|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPCP31B10.05 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPCP31B10.05 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Probable tyrosyl-DNA phosphodiesterase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCP31B10.05 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISS]
    Biological Process: single strand break repair [IMPLink to PubMed article]
    Molecular Function: 3'-tyrosyl-DNA phosphodiesterase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLEPEKRR QHEDKSNEII DSPIFLNKIS ALPESENVHC LLLKQLIGSP QLKQTWQFNF  60
   61 CVDLNFLLEN MHASVFPTVD VRITHGYDSK SDSLARLTAQ MNHCPVNVKL YSVYVPMWGT 120
  121 HHSKIMVNFF KDDSCQIVIH TANLVEPDWI GMSQAIFKTP LLYPKANDSL STSSVPEYGN 180
  181 PSKIRKHEGS LDIKDDRNCD IIDVDSAFEN FKHKSDTRSS DDLGVIGRQF QQDFLAYLKN 240
  241 YRHTYELIEK LKMYDFSAIR AIFIGSVPGK FEGEEESSWG LGKLKKILKM LEKDSKKDEK 300
  301 TKFEESDICI SQCSSMGSFG PKQEYIAELT DGFGCQRGNW KFLFPTVKEV QQSMLGWQSG 360
  361 SSIHFNILGK TAASQVETLK KGKNLCKWVA MKAGRQRVAP HIKTYMRFSN DGELLRWVLV 420
  421 TSANLSKPAW GTLEGHKAKS RSTRGLRIRS YEAGVLLYPK LFEESQRAPC IMTPTYKTNT 480
  481 PNLDEKRREF YGKRVIGVRM CWDFPPVEYE DKDEIWSPVI NRTDKDWLGY VWPPNW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..536] PSI-BLAST 154.0 human Tyrosyl DNA phosphodiesterase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3'-tyrosyl-DNA phosphodiesterase activity
    		•  1.46693175347055 bayes_pls_golite062009
  • tyrosyl-DNA phosphodiesterase activity
    		•  1.46693175347055 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.41591686174898 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.29668490323599 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.29429720882252 bayes_pls_golite062009
  • catalytic activity
    		•  1.29236214516383 bayes_pls_golite062009
  • binding
    		•  1.26667168593698 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.926017334343152 bayes_pls_golite062009
  • DNA binding
    		•  0.840595330626189 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.235198647671849 bayes_pls_golite062009
  • protein binding
    		•  0.162885453822356 bayes_pls_golite062009
  • kinase activity
    		•  0.10314500262782 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle