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Protein Overview: gef3

General Information:
Name(s) found: gef3 / SPBC29A3.17 [Sanger Pombe]
Description(s) found:
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  • pir||T40088 RhoGEF domain containing protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74626735|sp|O59679.1|GEF3_SCHPO RecName: Full=Rho guanine nucleotide exchange factor gef3 [NCBI NR]
  • gi|3006153|emb|CAA18394.1| RhoGEF Gef3 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112637|ref|NP_595845.1| RhoGEF Gef3 [Schizosaccharomyces pombe] [NCBI NR]
  • RhoGEF Gef3 [Sanger Pombe]
  • Rho guanine nucleotide exchange factor gef3 OS=Schizosaccharomyces pombe GN=gef3 PE=2 SV=1 [Swiss-Prot]
  • RHOGEF DOMAIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR: O59679; [pompepVF.fasta]
  • RHOGEF DOMAIN CONTAINING PROTEIN: O59679; [pompepV13]
  • RhoGEF domain containing protein [pompep4896]
  • |||RhoGEF [pompepnew.fasta]
  • SPBC29A3.17 protein [4896.FASTAC]
  • |gef3||RhoGEF|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • RhoGEF domain containing protein [Schizosaccharomyces pombe]gi|3006153|emb|CAA18394.1| SPBC29A3.17 [Schizosaccharomyces pombe]gi|7493290|pir||T40088 RhoGEF domain containing protein - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O59679) RhoGEF domain containing protein [pompep4896_normal_reversed]
  • |gef3||RhoGEF Gef3|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC29A3.17 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC29A3.17 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Rho guanine nucleotide exchange factor gef3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gef3 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 525 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of Rho protein signal transduction [IEA]
    regulation of catalytic activity [ICLink to PubMed article]
    Molecular Function: Rho guanyl-nucleotide exchange factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNPRMFQSR GKRVVSDSLP IANSTHTLED TLKLRPDWTI ALSQHETETR STRTSCSTTT  60
   61 ESTIAMRSKQ KAIISVLEEF RDSEAAYVHD LHVAQRYYAD RLSDRVKKSE WKDVFEIFLV 120
  121 LCKQASLFEI EMHKSLNDEI NYILDDQDAC LKPKPSVAQL FLSWLPKLSA VYGRYCVIQE 180
  181 NIGKKVEKWM KNSSISEYLQ ECDSMAKIES NSWNLDSFLV KPVQRFLKYP LLLNQLYRSA 240
  241 SLGIISDYVL LGEACHKSEI ASQRMNELKR RRDIIITALD SVSNSQEVLL LSTDSIDKKI 300
  301 AKLQNSTNIF YVPEHEPILA FVHQLSSSYT NLLNLRSAIC DWLKFSRYHY LKFFTFVEAY 360
  361 SVFCKDTKSA DKWALISVAL DNIAKGAVLR LTEQCQTSVL RPISNGILFF RNPLCVTDVW 420
  421 IKKATAFSKR RQSQVFEEDL ESFPLLSNCL LEELPLFLEM ARNVTDECIL AFAQIQATFY 480
  481 DTIQKVLEPV VAKFNLTDHQ DIPSIESIMD FTSLRSSMES SPKSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..431] PSI-BLAST 49.0 No description for 2pz1A was found.
    2 View Details [432..525] PSI-BLAST 30.221849 No description for 2ficA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle