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Protein Overview: tps2

General Information:
Name(s) found: tps2 / SPAC3G6.09c [Sanger Pombe]
Description(s) found:
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  • pir||T38728 probable trehalose-phosphate synthase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74581971|sp|O14145.1|TPS2_SCHPO RecName: Full=Trehalose-phosphatase; AltName: Full=Trehalose-6-phosphate phosphatase; Short=TPP; AltName: Full=Trehalose synthase complex catalytic subunit tps2 [NCBI NR]
  • gi|2408080|emb|CAB16285.1| trehalose-phosphate synthase Tps2 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19115887|ref|NP_594975.1| trehalose-phosphate synthase Tps2 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • trehalose-phosphate synthase Tps2 [Sanger Pombe]
  • Trehalose-phosphatase OS=Schizosaccharomyces pombe GN=tps2 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE TREHALOSE-PHOSPHATE SYNTHASE: O14145; [pompepVF.fasta]
  • Putative trehalose-phosphate synthase [pompep4896]
  • |||glycosyl transferase family 20 [pompepnew.fasta]
  • SPAC3G6.09c protein (EC 3.1.3.12) [4896.FASTAC]
  • |||glycosyl transferase family 20|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative trehalose-phosphate synthase [Schizosaccharomyces pombe]gi|2408080|emb|CAB16285.1| SPAC3G6.09c [Schizosaccharomyces pombe]gi|7493110|pir||T38728 probable trehalose-phosphate synthase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • (O14145) Putative trehalose-phosphate synthase [pompep4896_normal_reversed]
  • |tps2||trehalose-phosphate synthase Tps2 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC3G6.09c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC3G6.09c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Trehalose-phosphatase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tps2 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 849 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: trehalose biosynthetic process [ISSLink to PubMed article]
    dephosphorylation [ICLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    trehalose-phosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSGAQGNTQ SAAYKRIVNV SRNFQFKAAL NKDTREWTFQ HRSSGTALYS AIASLGDPSS  60
   61 PWDAVYVASP GPVQISEGND HTVETKIDEA AVVHRSSSIV ISPEDQEIFL KKATEYYRKK 120
  121 NIEADIVPVW GKVQRVPQAK SSSATITPSV SNKLSTAYQS IKSEALKDGP MYADSVLWDV 180
  181 LHYRIPTLDG YQQHNLWKNF TRWSQYFADN IVSNYRPGDL ILIHDYSLFL LPRLIRKQLS 240
  241 DAPIVFFLHA PFCTSEVFRC LSKRAEILKG VLASNVIAMQ TDSYTRHFLS TCSNVLGLET 300
  301 TSTHIDTSDG FRVVVFSSHV SIDVPRVYSR CNSKPVSLKI QQLKSLYPSD KKLIVGRDQL 360
  361 TKACGVTHKL RAFRELLIHF PKWRGHVVLI QITSLPVGNN YSNEELKKTE NLVAQINSEF 420
  421 GSLDYTPVIH FHQLLDPDEY YALLSVANIA CVSSVRDSMN TMALEYVACQ QKNKGSLILS 480
  481 EFSGTAELLL SAYLVNPYDY SRFAETINYC LNMTEKERER RFSSLWKQAT SQSSQQWIYK 540
  541 LINRAAYEVK ALESHMTTPL LTYNILIKPY RNAKRRLFLL DYDGTLIESA RNSIDAVPTD 600
  601 RLLRTLKRLA SDSRNIVWIL SGRSQKFMEE WMGDISELGL SSEHGSAIRP PLAGSWSSCA 660
  661 ENLDLSWKDT VRDFFQYYVE RTPGSYIEEK KHSISWCYQN ANTTYSKFQS LECQTNLEDM 720
  721 LKHYDVEISP AKSFLEVHPN YLNKGSIVRR ILKRSGSVDF VFCAGDDKTD ENMFEVFLPT 780
  781 AFSNSHLIDE IDSTEYSGSH HTDDNSDANK VENVKVATFR VHIGLTDKPT LSDYHLPAPR 840
  841 DLGELLHNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..560] PSI-BLAST 67.154902 Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
    2 View Details [561..849] PSI-BLAST 27.522879 Crystal structure of NYSGRC target T1436: A Hypothetical protein yidA.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
    		•  11.2045941324603 bayes_pls_golite062009
  • glucosyltransferase activity
    		•  8.25064561355471 bayes_pls_golite062009
  • UDP-glucosyltransferase activity
    		•  8.0463972704113 bayes_pls_golite062009
  • trehalose-phosphatase activity
    		•  7.58500038184065 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  3.70184884300914 bayes_pls_golite062009
  • catalytic activity
    		•  2.65148466065976 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.62403914335522 bayes_pls_golite062009
  • transferase activity
    		•  2.18054407163329 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  2.13085705769565 bayes_pls_golite062009
  • binding
    		•  0.86799881302731 bayes_pls_golite062009
  • carbohydrate phosphatase activity
    		•  0.78952375993773 bayes_pls_golite062009
  • UDP-N-acetylglucosamine 2-epimerase activity
    		•  0.690032302126686 bayes_pls_golite062009
  • glycogen phosphorylase activity
    		•  0.607220464589157 bayes_pls_golite062009
  • phosphorylase activity
    		•  0.296436712681472 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  0.253888301381021 bayes_pls_golite062009
    2
    Term Confidence Notes
  • trehalose-phosphatase activity
    		•  3.78859922218487 bayes_pls_golite062009
  • catalytic activity
    		•  1.55296860681783 bayes_pls_golite062009
  • binding
    		•  0.54369553186176 bayes_pls_golite062009
  • hydrolase activity
    		•  0.385402333062566 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.263520144636139 bayes_pls_golite062009
  • phosphatase activity
    		•  0.159899259988948 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.103902756538853 bayes_pls_golite062009
  • DNA binding
    		•  0.0142681844140111 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle