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Protein Overview: SPCC663.10

General Information:
Name(s) found: SPCC663.10 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • methyltransferase, DUF1613 family [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 502 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: tRNA methylation [ISS]
    Molecular Function: methyltransferase activity [ISS]
    tRNA (uracil) methyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVPAYWKPR EPKNALTCDP PVPYDLQSSY QWQSILEHDT CYAAEVFDKM MIELVYHPER  60
   61 TSSVIMRTDI ILDSQEDDSI LNKQKSVFEN LDERYQISRW IDRRIIPRNT NLDATMDQTV 120
  121 VVLHEKLEND RILMYLPHLD KSLEQPYNHL PYYHPAVAGI AFHYKGSSVE VLYLVEKDFQ 180
  181 RELSSRLLRT AHMLLLVLHK HCKGAVEGYQ KRMLHDTVVE RNKFQDTYVI LKDKYAKQLV 240
  241 DNWVEKTDPG KHVFEDLAIA AFLIELWKQT YSSNKEFSFV DVGCGNGLLV YLLLMEGYNG 300
  301 YGFDARKRKS WETYPLWVQV KLYEKVLVPY FLHDFETKIP FPQLPAGFTM SAANIHDGRF 360
  361 SENSFLIGNH ADELTPYLPI LARLNQKCYF MSIPCCVHDL TGAKISWALP KPRNPKHGGR 420
  421 YAMYIEWLMQ LSEEVGWNIE VEPLRIPSTR NYALIGRKLL SNDLLHSSLS TDALYDIVEK 480
  481 NHGSQGFFVH AMQVAAANSR SH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..208] deduced N/A No confident structure predictions are available.
    2 View Details [209..502] FFAS03 1.1 Crystal structure of thiopurine S-methyltransferase.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • methyltransferase activity
    		•  3.68431317301075 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.64494850793256 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  3.60853685152199 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.51986359093355 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.91374296950366 bayes_pls_golite062009
  • transferase activity
    		•  2.67612625778122 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  2.666651371662 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  2.63941856307703 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  2.21653466290591 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  2.14987271695676 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  1.99340565364513 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  1.99340565364513 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  1.77527486495102 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  1.64765900536818 bayes_pls_golite062009
  • tRNA (cytosine)-methyltransferase activity
    		•  1.54257365884902 bayes_pls_golite062009
  • tRNA (cytosine-5-)-methyltransferase activity
    		•  1.54257365884902 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  1.27753381141602 bayes_pls_golite062009
  • catalytic activity
    		•  1.16970557486814 bayes_pls_golite062009
  • tRNA (adenine)-methyltransferase activity
    		•  0.966274102011523 bayes_pls_golite062009
  • tRNA (adenine-N1-)-methyltransferase activity
    		•  0.966274102011523 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.953292160159369 bayes_pls_golite062009
  • DNA binding
    		•  0.878229880745235 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  0.735680462496249 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.668500493633294 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  0.51222176401398 bayes_pls_golite062009
  • binding
    		•  0.486361285495359 bayes_pls_golite062009
  • RNA binding
    		•  0.413112349791396 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.374941249737739 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.300104233454652 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.286806504860858 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  0.0180486171234466 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle