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Protein Overview: atg12

General Information:
Name(s) found: atg12 / SPAC1783.06c [Sanger Pombe]
Description(s) found:
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  • gi|6714826|emb|CAB66169.1| autophagy associated protein Atg12 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|62899896|sp|Q9US24.1|ATG12_SCHPO RecName: Full=Autophagy-related protein 12; AltName: Full=Autophagy-related ubiquitin-like modifier atg12 [NCBI NR]
  • gi|19114573|ref|NP_593661.1| autophagy associated protein Atg12 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • pir||T50108 yeast APG12 Protein conjugation factor homolog [imported] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • autophagy associated protein Atg12 [Sanger Pombe]
  • Autophagy-related protein 12 OS=Schizosaccharomyces pombe GN=atg12 PE=2 SV=1 [Swiss-Prot]
  • SIMILAR TO S. CEREVISIAE APG12 AUTOPHAGY PROTEIN INVOLVED IN CYTOPLASM TO VACUOLE TARGETING: Q9US24; [pompepVF.fasta]
  • Similar to yeast APG12 protein conjugation factor [pompep4896]
  • |||similar to S. cerevisiae APG12 [pompepnew.fasta]
  • SPAC1783.06c protein [4896.FASTAC]
  • |||similar to S. cerevisiae YBR217W|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • similar to yeast APG12 Protein conjugation factor [Schizosaccharomyces pombe]gi|6714826|emb|CAB66169.1| SPAC1783.06c [Schizosaccharomyces pombe]gi|11359339|pir||T50108 yeast APG12 Protein conjugation factor homolog [imported] - fission yeast (Schizosacc [nrdb_11152004_Chlamydomonas]
  • (Q9US24) Similar to yeast APG12 protein conjugation factor [pompep4896_normal_reversed]
  • |apg12||autophagy protein Apg12|Schizosaccharomyces pombe|chr 1|||Manual [pombe030305.revfasta]
  • |atg12|apg12|autophagy associated protein Atg12 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC1783.06c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC1783.06c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier atg12) [nr-271106-contam.fasta]
  • |atg12|apg12|autophagy associated ubiquitin-like modifier Atg12|Schizosaccharomyces pombe|chr 1|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Ubiquitin-like protein ATG12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atg12 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 132 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: autophagic vacuole assembly [ISSLink to PubMed article]
    ascospore formation [IMPLink to PubMed article]
    autophagy [IMPLink to PubMed article]
    C-terminal protein lipidation [ISS]
    protein targeting to vacuole [ISSLink to PubMed article]
    macroautophagy [IC]
    cellular response to nitrogen starvation [IMPLink to PubMed article]
    Molecular Function: protein tag [ISS]
    Atg8 ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGLVDQQEL EKRLATEEDS QNEDIENQLP SIETIINTYR EKENRRVNLR FKAIGRTPLL  60
   61 RKTVFSINAS QRFEKVTRFL KKELGLPMNS SLVLYVNSSF APSPDEIVGN LYDNFAIDSH 120
  121 LLINYCINVA FG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] PSI-BLAST 46.221849 Golgi-associated ATPase enhancer of 16 kD, Gate-16

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.63877637096497 bayes_pls_golite062009
  • protein binding
    		•  2.0758030814092 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.00343080662821671 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle