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Protein Overview: SPBP8B7.08c

General Information:
Name(s) found: SPBP8B7.08c [Sanger Pombe]
Description(s) found:
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  • pir||T40802 conserved hypothetical protein SPBP8B7.08c - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582826|sp|O94257.1|LCMT1_SCHPO RecName: Full=Leucine carboxyl methyltransferase 1; AltName: Full=Protein phosphatase methyltransferase 1 [NCBI NR]
  • gi|3810832|emb|CAA21793.1| leucine carboxyl methyltransferase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113307|ref|NP_596515.1| leucine carboxyl methyltransferase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • leucine carboxyl methyltransferase [Sanger Pombe]
  • Leucine carboxyl methyltransferase 1 OS=Schizosaccharomyces pombe GN=ppm1 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE LEUCINE CARBOXYL METHYLTRANSFERASE, HAS SIMILAR TO HUMAN LCMT AND YEAST PPM2: O94257; [pompepVF.fasta]
  • PUTATIVE LEUCINE CARBOXYL METHYLTRANSFERASE, HAS SIMILARITY TO HUMAN LCMT AND YEAST PPM2: O94257; [pompepV13]
  • Conserved hypothetical protein [pompep4896]
  • |||putative leucine carboxyl methyltransferase [pompepnew.fasta]
  • SPBP8B7.08c protein (EC 2.1.1.-) [4896.FASTAC]
  • |||leucine carboxyl methyltransferase (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • conserved hypothetical protein [Schizosaccharomyces pombe]gi|3810832|emb|CAA21793.1| SPBP8B7.08c [Schizosaccharomyces pombe]gi|7490356|pir||T40802 conserved hypothetical protein SPBP8B7.08c - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||leucine carboxyl methyltransferase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O94257) Conserved hypothetical protein [pompep4896_normal_reversed]
  • |||leucine carboxyl methyltransferase Ppm1 |Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBP8B7.08c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Leucine carboxyl methyltransferase 1 (Protein phosphatase methyltransferase 1) [nr-271106-contam.fasta]
  • hypothetical protein SPBP8B7.08c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Leucine carboxyl methyltransferase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ppm1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 310 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    Biological Process: protein complex assembly [ISS]
    C-terminal protein amino acid methylation [ISSLink to PubMed article]
    cellular protein complex assembly [ISS]
    Molecular Function: C-terminal protein carboxyl methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDITETDLDA LKCRSSATKS GYIHDPFIKF FSPSRNSHKP PIINRGTYVR TWSIDHILQK  60
   61 FIESFDGKKQ IISLGAGTDT RVFRYISEYG PENLKFIEFD FYPNCIRKIR TIEKHEALKQ 120
  121 NIGDYVVDIS GGSLVSGSLD IYSYDIREIV HKGFPGFVDF SLPTIVLSEC CLCYLEPEEA 180
  181 SSLCRWFQNM FATSGIVVYE PIQGMDNFGK MMKANLSARG VILKTLDCYE TTEQQRMRFL 240
  241 DYGYSEVIAE DFLTIEETWI PIEEKKRTMS IEMLDELEEW QLLAKHYCLT FAATENLWNQ 300
  301 IILQLPHLKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..310] PSI-BLAST 56.69897 Structure of PPM1, a leucine carboxy methyltransferase involved in the regulation of protein phosphatase 2A activity

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein methyltransferase activity
    		•  4.65643463984431 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  4.4632173842967 bayes_pls_golite062009
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.67177992319602 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  3.4768933204909 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  2.91440420216458 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  2.91440420216458 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.45397942930513 bayes_pls_golite062009
  • transferase activity
    		•  2.22303238506686 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  2.07640017323617 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  1.63765148226572 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  1.52139371235933 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  1.40758086578142 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  0.817509452491588 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • binding
    		•  0.348263200169904 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  0.328046788565125 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  0.230719796976667 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle