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Protein Overview: set8

General Information:
Name(s) found: set8 / SPAC3C7.09 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • lysine methyltransferase Set8 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 429 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: protein amino acid methylation [ISSLink to PubMed article]
    Molecular Function: protein-lysine N-methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIKYNELVN QFAPGAKQIT IKKIRKKGNG IFSLNRYTSG TVLLEVPLEN IICRKTVEQF  60
   61 RNSCDKFASI ATLEEWNDMS FRTQAMLFLC YLWLGIQPRT NKWDKFLTVL PLSINTPAQW 120
  121 PEKEVYSLQG TSIFNPVCVK RKILQQEWLS LNQRYSDSWP SKITLPKWVH ADALFHSRCL 180
  181 ESPFKDPVLA PVIDLCNHSS KSNAKWSFSE DAMQLYLDKD IDENEEVTIN YGSEKGSAEF 240
  241 LFSYGFLPEP EGDRITNVMK LLIPEDSNDS LDLAKRRSCK TPPMIEFVSD SSGELWWHAP 300
  301 FLFFSVLNVE DFTNFKMVCD ESKAQTVDWE FEGQKCSVED LPKLVQLSPK RDLYILRVFC 360
  361 LAEQLADAAL NTNIENMYNP TERRSESVEL LKRESFLLKK VLLYLRDVIS KLLKSKVVVE 420
  421 FIHSQTIES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..429] PSI-BLAST 59.0 RuBisCo LSMT C-terminal, substrate-binding domain; RuBisCo LSMT catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone methyltransferase activity
    		•  6.20878333364554 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  6.08778683840554 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.98411678860954 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K9 specific)
    		•  3.54138873512018 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.69428385009711 bayes_pls_golite062009
  • methyltransferase activity
    		•  2.33114816345072 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.25175257044903 bayes_pls_golite062009
  • binding
    		•  1.67469558504376 bayes_pls_golite062009
  • transferase activity
    		•  1.35661693913815 bayes_pls_golite062009
  • protein binding
    		•  1.07532079834012 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.588883714202448 bayes_pls_golite062009
  • catalytic activity
    		•  0.414641636618101 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle