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Protein Overview: jmj2

General Information:
Name(s) found: jmj2 / SPAC1002.05c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • histone demethylase Jmj2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 715 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [ISSLink to PubMed article]
    Biological Process: chromatin remodeling [IMPLink to PubMed article]
    regulation of gene-specific transcription from RNA polymerase II promoter [IEPLink to PubMed article]
    histone demethylation [IDALink to PubMed article]
    negative regulation of gene-specific transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    Molecular Function: DNA binding [ISSLink to PubMed article]
    zinc ion binding [ISS]
    histone demethylase activity [IDALink to PubMed article]
    histone demethylase activity (H3-dimethyl-K4 specific) [IDALink to PubMed article]
    histone demethylase activity (H3-trimethyl-K4 specific) [IDALink to PubMed article][IMPLink to PubMed article]
    histone demethylase activity (H3-K36 specific) [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSTFHQTS PSFVQYTHAT DKLKPAPHGM NTRGNNLSSM SKNTGQRKQR SKSIHGLPVA  60
   61 PVFYPDKEEF QDSIGYINKI APIGEKYGII KIVPPAGWNP PMQLDMNKFS FRTRRQDLHM 120
  121 MDLRFREIVS YDERVYRFFC NLGMELPESF FISNTSIDLY SLMRCIDSHA SLSEKELKVH 180
  181 VWKRILRELS IPFTNASLKE ASDLYLRYIF PFEDFVRKYQ TSEDQCFETD LFPKFFTKDE 240
  241 HSNISIKDQK TSKQFNPETN ESVGILQNQE SKRNEQIKQQ YMPADNFGSN DNHSHNKKRR 300
  301 LSSLSTNNNH LCDNCHKPVN CEVEDTCKEA YCTKCIINPY EFGFETGNYY TLSNFEKYCD 360
  361 NFKKNYFSKF KDSEITEDIV EKEYWKLVKD NNTSLEVEYG ADLSTLDQGS AFPSLAKNPV 420
  421 NPYSKDTWNL NVIASTNGSL LSYIDNPVSG ITCPWLYVGM CFSTFCWHVE DNYTYSVNYQ 480
  481 HYGDTKLWYG IPGDQAERFE RAALDIAPDL VKKQKDLLYQ LATMINPDEL QKRGVDVYFI 540
  541 DQGPNEFVIT FPKSFHAGIN HGFNINEAVN FAPKDWLLNG FSLNGVLKYQ SLLKPPVLSH 600
  601 DMLVYNLATN PASEISVSEL RPWVHEAVKR ELGIRIMIRG RYDLKEILYR ELMEDAENWQ 660
  661 CQHCKAFSYF SQVACSCKSI TVCPLHIEYL CKCDLSNKTL RLKVDDNELQ KLLSY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..106] FFAS03 3.61 No description for 2oq6A was found.
    2 View Details [107..257] PSI-BLAST 23.522879 DNA-binding domain from the dead ringer protein
    3 View Details [258..335] deduced N/A No confident structure predictions are available.
    4 View Details [336..612] PSI-BLAST 66.69897 No description for 2oq6A was found.
    5 View Details [613..715] MSA 2.169987 View MSA. Confident ab initio structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle