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Protein Overview: SPAC26H5.03

General Information:
Name(s) found: SPAC26H5.03 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • WD repeat protein Cac2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 512 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nuclear chromatin [IC]
    CAF-1 complex [IDALink to PubMed article]
    nuclear replication fork [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    chromatin remodeling complex [IDALink to PubMed article]
    Biological Process: ascospore formation [IMPLink to PubMed article]
    negative regulation of histone acetylation [IMPLink to PubMed article]
    positive regulation of histone H3-K9 methylation [IMPLink to PubMed article]
    heterochromatin maintenance [IMPLink to PubMed article]
    positive regulation of chromatin silencing at silent mating-type cassette [IMPLink to PubMed article]
    positive regulation of chromatin silencing at centromere [IMPLink to PubMed article]
    protein localization in nucleus [IMPLink to PubMed article]
    nucleosome assembly [IPILink to PubMed article]
    DNA replication-dependent nucleosome assembly [ICLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAEVLQIRW HYDANDDHTP IYSVDFQKNS LNKFATCGGD SKIRIWQLIT SESSTKVEYL  60
   61 STLSRHTQAV NVVRFNPEGN ILATAGDEGT IMLWVPTNTP ITTLADDAEE LALAKEYWKV 120
  121 KIVCRSMGSE IYDLCWSVDS NFLIAGAMDN SLRLYDAHTG QLLTQKFDHS HYVQGVCWDP 180
  181 LNQYIVSESS DRSICLYEIQ EEKKNPKKFQ LVLKSRICRI EYNVTKFELI SVTKPLNNDE 240
  241 SSGISEPIET SNNNESPVSK HEALSSTANI VKDGSLERTE PPNSLNSKIS YSLYCNETLV 300
  301 SFFRRPAFSP DGLLLVTPAG RLRPHGQPNF EVPYTAYIYT RGSITKQPVA CLNGFKKPVI 360
  361 AVRFSPIHYE LNSFSNFSFT SVSFNLPYRM VFAVACQDAV YIYDTQTCKP FYRAVNLHYS 420
  421 NLTDIAWNDD GNVLLMTSID GFCSVITFEP GELGVKSQHK ISLPEKRSAS PSSIDDSQDN 480
  481 TAGGPATTTL IPRKVESSKV SKKRIAPTPV YP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..512] PSI-BLAST 43.39794 Actin interacting protein 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.2778252170547 bayes_pls_golite062009
  • protein binding
    		•  1.24173112731149 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.22384651674093 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.19593750149343 bayes_pls_golite062009
    		• 0.92526678064403 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.90664265656758 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • actin binding
    		•  0.529861581509437 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.485054404024611 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.412354662535711 bayes_pls_golite062009
  • chromatin binding
    		•  0.145491963066342 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0515743510044684 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle