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Protein Overview: SPBC1861.04c

General Information:
Name(s) found: SPBC1861.04c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • RNA-binding protein Prp24 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1014 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    U6 snRNP [ISSLink to PubMed article]
    Biological Process: RNA splicing, via transesterification reactions [ISSLink to PubMed article]
    spliceosome assembly [ISSLink to PubMed article]
    assembly of spliceosomal tri-snRNP [ISSLink to PubMed article]
    Molecular Function: snRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQIQDLKDE NVEMDIDPQE QNEKKPLLLD ELTKFTILHP YNYDSHIKLI EELKRLDKKK  60
   61 ELSEARKTFQ SIFPLSEDLW VDYLLDECKN CRTLDDYVRI KTLFDLAVQD YLSIKIWCMY 120
  121 LEFTLNLMDT SSFEQEQSEL NGVITLTDAH SLFERAYQTC KFHFSKSQCV WTLYLEFLQT 180
  181 FGDALFEGEE EQEIVFKNKI YDFHIDRLKL PHEQIEETFT SLSTFVTNNW SPSEYEDVMV 240
  241 KSNKVYETTL KRNAKIFNKE LLLNSANHSL EAYMDLINDE SRRSTAELQY ITTLYERAIV 300
  301 LYPLIPELWL QYTAWLSKVD FSSSQASSVA ERATRNCSWI GRIWSIKLTY MTLSGASTSA 360
  361 VCEEKDRCLN SNLLVNFDEV IDFFSGFLKA CLYLSSNEDK PQEFLKHQIH KVEDYLRKNH 420
  421 KGSKDARMRI ELSKIYLYSE ISDFESVEKC WSDMFHDFQN QALYWISRYI STMKYNPELA 480
  481 AETLKKSLYK NVDQPQLLFQ FYQSIMDLNN DCFTNTSHLY DVLNAQRISF KRQLDSFAEE 540
  541 TKQTVENTEP LKVPQADDTA ALSKKRKPGQ EGDVFKKSKP IEQHRNREEL TVLVTNLPSD 600
  601 ISENELKIFF KDCGNIIRIF ILEDNQKDVK VAQIEFSETS EVLAAKTRDL KSIRGHEISV 660
  661 QIHVDTNLYV TNFPPTYDEL DITKLFSAYG NVVDVRFPSL RYNTNRRFCY VQMRKPDEAH 720
  721 NALQLHKKLL EEKYPIQVFI SDPLRRTPRS GAVYEGRELY VTNIDFKVNE KDVETFFRDY 780
  781 GQVESVRIPK RFNQHKGFGY VVMTTNQDAE NALSAAGKQL GNRVLNVVLS KPRESLEKTR 840
  841 VSSNDNRTLA KSFETTESNK MSTPKKSFEQ IKSKSLGVTN VDGTVNEARL RSLFESYGKL 900
  901 YRVVLHPEHE GAVVEFLDIH DAGKASLALE GHEIGGRLLH ITTVNEMMHN VPSSMNHSDY 960
  961 NTSATRPRRL GSRTFQGFNS NHSNINSKKD DLDDKEMQID APKSNDDFRK MFLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..475] PSI-BLAST 54.045757 No description for 2ooeA was found.
    2 View Details [476..575] deduced N/A No confident structure predictions are available.
    3 View Details [576..852] PSI-BLAST 28.30103 No description for 2ghpA was found.
    4 View Details [853..1014] PSI-BLAST 37.0 Nuclear ribonucleoprotein A1 (RNP A1, UP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  2.76684454218635 bayes_pls_golite062009
  • binding
    		•  2.57186536498101 bayes_pls_golite062009
  • protein binding
    		•  1.83529176977066 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.26149030245805 bayes_pls_golite062009
  • DNA binding
    		•  0.9531600253493 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.93037889019021 bayes_pls_golite062009
  • signal sequence binding
    		•  0.8574224889202 bayes_pls_golite062009
  • transcription factor activity
    		•  0.374364600772076 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.81920018903278 bayes_pls_golite062009
  • binding
    		•  3.49612884560266 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • protein binding
    		•  1.32954276279597 bayes_pls_golite062009
  • structural molecule activity
    		•  1.29928829870122 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07788694919471 bayes_pls_golite062009
  • DNA binding
    		•  0.978604858165557 bayes_pls_golite062009
  • snoRNA binding
    		•  0.642109402325711 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.591700155096213 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.425042944899091 bayes_pls_golite062009
  • transcription factor activity
    		•  0.234742017105535 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle