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Protein Overview: SPBC646.08c

General Information:
Name(s) found: SPBC646.08c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • oxysterol binding protein [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 516 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: steroid biosynthetic process [ISSLink to PubMed article]
    regulation of endocytosis [ISS]
    Molecular Function: oxysterol binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNPNQAIKK ENEPIQVENP TELVRDDGEV EGYQKEEGKF KLVLSILKQC IGVKDIASLR  60
   61 FSLPAQLLEP VGNLEYWNYV DRPDYFAVMG DSDDELERML GVLRWWFTKD LRFVRGRVVK 120
  121 PYNSVLGEFF RCKWVVTDPT VREDHTLDPD SSQLPTYKTE YSETTKFPLG KSYRPKASRT 180
  181 TSSQSVASTM TKSSTKTSKK KSSKKNSKSE SNQDSSNDRS STAPSTAESN NEHLSSSQKS 240
  241 KHSIVFMAEQ TSHHPAVSAF YVTCPSKGIE VYGQDQIAVG FTGTSFKVCA GDLNKGVYVR 300
  301 FNKRDNEEYL CTHPSASVGG ILRGNLHINL LDSTVILCPK TRIKTIITYI EERWLGKPRS 360
  361 LVEGVCYRYD PSNDTIDSIK AVPKENILAT FKGNWRNCIF YSYAGESESR MLVDLNELDL 420
  421 VHKRCPPLDK QFPFESRKIW FPVTHNILAK HYTQATKAKQ EIEDQQRQAS AAREESHTEW 480
  481 KPRFFVPDEK EGRPTLTEEG KKVLEQSLSD EYIHGS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..191] FFAS03 5.89 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
    2 View Details [192..516] PSI-BLAST 74.221849 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
  • binding
    		•  0.958372296392311 bayes_pls_golite062009
    		• 0.35288515581255 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle