YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC646.08c
Organism:	Schizosaccharomyces pombe
Length:	516 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC646.08c.

Description	E-value	Query Range	Subject Range
gi\|71017757, gi\|... - gi\|71017757\|ref\|XP_759109.1\| hypothetical protein UM02962.1 [Ustilago maydis 521], ref\|XP_400577.1\| ...	422.0	[0..8]	[505..22]
gi\|39974001, gi\|... - gi\|39974001\|ref\|XP_368391.1\| hypothetical protein MG00853.4 [Magnaporthe grisea 70-15], gb\|EAA49195....	422.0	[0..22]	[512..3]
gi\|58257399 - gi\|58257399\|gb\|AAW69321.1\| oxysterol binding protein-like protein [Magnaporthe grisea]	420.0	[0..22]	[512..3]
gi\|46125325, gi\|... - gi\|46125325\|ref\|XP_387216.1\| hypothetical protein FG07040.1 [Gibberella zeae PH-1], gi\|42553756\|gb\|E...	405.0	[0..28]	[512..11]
gi\|90299349, gi\|... - gi\|90299349\|gb\|EAS28980.1\| hypothetical protein CIMG_07726 [Coccidioides immitis RS], gi\|119177621\|r...	361.0	[0..131]	[512..835]
gi\|38567327, gi\|... - gi\|38567327\|emb\|CAE76615.1\| related to oxysterol-binding protein [Neurospora crassa], gi\|32408555\|re... gi\|85074703 - gi\|85074703\|ref\|XP_965719.1\| hypothetical protein NCU00579 [Neurospora crassa OR74A]	352.0	[0..138]	[509..823]
gi\|66844308, gi\|... - gi\|70982312\|ref\|XP_746684.1\| oxysterol binding protein (Osh1) [Aspergillus fumigatus Af293], gi\|6684...	350.0	[0..138]	[512..790]
gi\|50750387 - gi\|50750387\|ref\|XP_421982.1\| PREDICTED: similar to Oxysterol binding protein-related protein 6 (OSBP...	349.0	[0..138]	[508..755]
OSBPL5 - oxysterol binding protein-like 5	348.0	[0..127]	[505..340]

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Predicted Domain #1

Region A:
Residues: [1-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNPNQAIKK ENEPIQVENP TELVRDDGEV EGYQKEEGKF KLVLSILKQC IGVKDIASLR  60
   61 FSLPAQLLEP VGNLEYWNYV DRPDYFAVMG DSDDELERML GVLRWWFTKD LRFVRGRVVK 120
  121 PYNSVLGEFF RCKWVVTDPT VREDHTLDPD SSQLPTYKTE YSETTKFPLG KSYRPKASRT 180
  181 TSSQSVASTM T

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.89
Match:	1zhtA
Description:	Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [192-516]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSSTKTSKKK SSKKNSKSES NQDSSNDRSS TAPSTAESNN EHLSSSQKSK HSIVFMAEQT  60
   61 SHHPAVSAFY VTCPSKGIEV YGQDQIAVGF TGTSFKVCAG DLNKGVYVRF NKRDNEEYLC 120
  121 THPSASVGGI LRGNLHINLL DSTVILCPKT RIKTIITYIE ERWLGKPRSL VEGVCYRYDP 180
  181 SNDTIDSIKA VPKENILATF KGNWRNCIFY SYAGESESRM LVDLNELDLV HKRCPPLDKQ 240
  241 FPFESRKIWF PVTHNILAKH YTQATKAKQE IEDQQRQASA AREESHTEWK PRFFVPDEKE 300
  301 GRPTLTEEGK KVLEQSLSDE YIHGS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.221849
Match:	1zhtA
Description:	Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
sterol binding	3.12877992228795	bayes_pls_golite062009
steroid binding	2.54679035876403	bayes_pls_golite062009
lipid binding	1.46539100663772	bayes_pls_golite062009
oxysterol binding	1.1738554488982	bayes_pls_golite062009
binding	0.958372296392311	bayes_pls_golite062009
	0.35288515581255	bayes_pls_golite062009
phospholipid binding	0.0867097353003303	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: