Protein Overview: spp42

General Information:
Name(s) found:	spp42 / SPAC4F8.12c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T38841 probable pre-mRNA splicing factor - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|74626636\|sp\|O14187.1\|SPP42_SCHPO RecName: Full=Pre-mRNA-splicing factor spp42; AltName: Full=Complexed with cdc5 protein 6 [NCBI NR] gi\|2440191\|emb\|CAB11062.1\| U5 snRNP complex subunit Spp42 [Schizosaccharomyces pombe] [NCBI NR] gi\|19114773\|ref\|NP_593861.1\| U5 snRNP complex subunit Spp42 [Schizosaccharomyces pombe 972h-] [NCBI NR] U5 snRNP complex subunit Spp42 [Sanger Pombe] Pre-mRNA-splicing factor spp42 OS=Schizosaccharomyces pombe GN=spp42 PE=1 SV=1 [Swiss-Prot] U5 SNRNA-ASSOCIATED SPLICING FACTOR; PRE-MRNA SPLICING FACTOR; SIMILAR TO S. CEREVISIAE PRP8: O14187; [pompepVF.fasta] Probable pre-mRNA splicing factor [pompep4896] \|spp42\|cwf6\|U5 snRNA-associated splicing factor [pompepnew.fasta] SPAC4F8.12c protein (Spp42 protein) (Cwf6 protein) [4896.FASTAC] \|spp42\|cwf6\|U5 snRNA-associated splicing factor\|Schizosaccharomyces pombe\|chr 1\|\|\|Manual [pombe041504.fasta] probable pre-mRNA splicing factor [Schizosaccharomyces pombe]gi\|2440191\|emb\|CAB11062.1\| SPAC4F8.12c [Schizosaccharomyces pombe]gi\|7492841\|pir\|\|T38841 probable pre-mRNA splicing factor - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas] (O14187) Probable pre-mRNA splicing factor [pompep4896_normal_reversed] \|spp42\|cwf6\|U5 snRNP complex subunit Spp42\|Schizosaccharomyces pombe\|chr 1\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] SPAC4F8.12c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] hypothetical protein SPAC4F8.12c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] Pre-mRNA-splicing factor spp42 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spp42 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	2363 amino acids
Gene Ontology:
Cellular Component:	U4/U6 x U5 tri-snRNP complex [ISS] U5 snRNP [ISS] spliceosomal complex [IEA]
Biological Process:	RNA splicing, via transesterification reactions [ISS] spliceosomal conformational changes to generate catalytic conformation [IGI]
Molecular Function:	RNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASLPPGNPP PPPPPPGFEP PSQPPPPPPP GYVKKRKNKT PAQSGNLEKQ LNERARKWRA  60
   61 SQKSKFGVKR KQGYVQTEKA DLPPEHLRKI MKDRGDMSSR KFRADKRSYL GALKYLPHAV 120
  121 LKLLENMPMP WEEYREVKVL YHVTGAITFV NESPRVIEPH FIAQWGTMWM MMRREKRDRK 180
  181 NFKRLRFPPF DDEEPPFSID QLLDLEPLEA IRMDLDEEDD APVMDWFYEN KALEDTPHVN 240
  241 GPTYRRWKLN LPQMANLHRL GYQLLSDLRD DNYFYLFNDN SFFTAKALNV AIPGGPKFEP 300
  301 LYKDEAPEME DWNEFNDIYK LIIRHPIKTE YRIAFPYLYN SRARSVALSE YHQPSNVFVP 360
  361 PEDPDLPAFF WDPIINPITS RQLTLHELDT SPEDSAIEED PNFEIPFDPF FHSEDIEFEH 420
  421 TASALILLWA PHPFNKRSGA TKRAQDVPLI KHWYLEHCPP NQPVKVRVSY QKLLKSHVMN 480
  481 KLHMAHPKSH TNRSLLRQLK NTKFFQSTSI DWVEAGLQVC RQGYNMLQLL IHRKGLTYLH 540
  541 LDYNCNLKPT KTLTTKERKK SRFGNAFHLM REILRLTKLI VDSHVQYRLG NIDAYQLADG 600
  601 LHYIFNHVGQ LTGMYRYKYR LMRQIRACKD FKHLIYYRFN TGPVGKGPGC GFWAPSWRVW 660
  661 LFFLRGIVPL LERWLGNLLA RQFEGRHSTG VAKQITKQRV DSHQDLELRA AVMNDILDMI 720
  721 PEGIRQGKSK TILQHLSEAW RCWKANIPWK VPGLPAPIEN MILRYVKSKA DWWTSVAHFN 780
  781 RERIRRGATV DKTVAKKNLG RLTRLWLKAE QERQHNYLKD GPYVTADEAV AIYTTFVHWL 840
  841 ESRRFQPIPF PPLSYKHDTK LLVLALERLK EAYSVKGRLN QSQREELALV EQAYDNPHEM 900
  901 LSQIKRRLLT MRTFKEVGIE FMDMYSHLIP VYSVDPMEKI CDAYLDQYLW FEADRRHLFP 960
  961 SWVKPSDSEP PPLLVYKWCQ GINNLTDVWE TSNGECNVLM ETRLSKVFEK VDLTLLNRLM1020
 1021 SLLMDTNLAS YASAKNNVVL SYKDMSHTNS YGLVRGLQFS SFIWQFYGLV LDLLILGLQR1080
 1081 ATEIAGPADA PNDFLHFKDQ ATETSHPIRL YTRYIDKVYI MFRFTDEESR DLIQRFLNEN1140
 1141 PDPTNSNVVN YSKGKKNCWP RDARMRLMKH DVNLGRAVFW EIRNRLPRSL TTLEWEDTFP1200
 1201 SVYSKDNPNL LFSMTGFEVR ILPKIRQNEE FSLKDGVWNL TDNRTKQRTA QAFIRVTEDG1260
 1261 INQFGNRIRQ ILMSSGSTTF TKIANKWNTA LIALMTYYRE AAISTPELLD LLVKCESKIQ1320
 1321 TRVKISLNSK MPSRFPPAVF YSPKELGGLG MLSMGHVLIP QSDLRWSKQT DTGITHFRSG1380
 1381 MTTNGEHLIP NLYRYIQPWE SEFIDSQRVW AEYAMKRQEA LQQNRRLTLE DLEDSWDRGI1440
 1441 PRINTLFQKD RHTLAYDKGW RVRTEFKQYQ LLKNNPFWWT SQRHDGKLWQ LNNYRVDVIQ1500
 1501 ALGGVEGILE HTMFKATGFP SWEGLFWEKA SGFEESMKFK KLTNAQRSGL NQIPNRRFTL1560
 1561 WWSPTINRAN VYVGFQVQLD LTGIMMHGKI PTLKISLIQI FRSHLWQKIH ESVVWDLCQV1620
 1621 LDQELESLQI ETVQKETIHP RKSYKMNSSC ADILLLAAYK WNVSRPSLLN DNRDVLDNTT1680
 1681 TNKYWIDVQL RFGDYDSHDI ERYTRAKFLD YSTDAQSMYP SPTGVLIGID LCYNMHSAYG1740
 1741 NWIPGMKPLI QQSMNKIMKA NPALYVLRER IRKGLQLYAS EPQEQYLSSS NYAELFSNQI1800
 1801 QLFVDDTNVY RVTIHKTFEG NLTTKPINGA IFIFNPRTGQ LFLKVIHTSV WAGQKRLGQL1860
 1861 AKWKTAEEVA ALIRSLPVEE QPRQIIVTRK GMLDPLEVHL LDFPNITIKG SELQLPFQAI1920
 1921 IKLDKINDLI LRATEPQMVL FNLYDDWLQS VSSYTAFSRL ILILRALNVN TEKTKLILRP1980
 1981 DKSIITKENH VWPNLDDQQW LDVEPKLRDL ILADYAKKNN INVASLTNSE VRDIILGMTI2040
 2041 TAPSLQRQQI AEIEKQGREN AQVTAVTTKT TNVHGDEMVV TTTSAYENEK FSSKTEWRNR2100
 2101 AISSISLPLR TKNIYVNSDN ISETFPYTYI LPQNLLRKFV TISDLRTQVA GYMYGKSPSD2160
 2161 NPQIKEIRCI ALVPQLGSIR NVQLPSKLPH DLQPSILEDL EPLGWIHTQS SELPYLSSVD2220
 2221 VTTHAKILSS HPEWDTKAVT LTVSYIPGSI SLAAYTVSKE GIEWGSKNMD INSDEAIGYE2280
 2281 PSMAEKCQLL LSDRIQGFFL VPEEGVWNYN FNGASFSPKM TYSLKLDVPL PFFALEHRPT2340
 2341 HVISYTELET NDRLEEDMPD AFA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: spp42

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: