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Protein Overview: spt5

General Information:
Name(s) found: spt5 / SPAC23C4.19 [Sanger Pombe]
Description(s) found:
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  • pir||T38274 probable transcription initiation protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74581925|sp|O13936.1|SPT5_SCHPO RecName: Full=Transcription elongation factor spt5; AltName: Full=Chromatin elongation factor spt5 [NCBI NR]
  • gi|2465160|emb|CAB16890.1| transcription elongation factor Spt5 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114103|ref|NP_593191.1| transcription elongation factor Spt5 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • transcription elongation factor Spt5 [Sanger Pombe]
  • Transcription elongation factor spt5 OS=Schizosaccharomyces pombe GN=spt5 PE=1 SV=1 [Swiss-Prot]
  • POSSIBLY INVOLVED IN CHROMATIN REMODELING; PUTATIVE GLOBAL TRANSCRIPTION FACTOR A; SIMILAR TO S. CEREVISIAE SPT5: O13936;Q9US64; [pompepVF.fasta]
  • PUTATIVE INVOLVEMENT IN CHROMATIN STRUCTURE: O13936;Q9US64; [pompepV13]
  • Putative involvement in chromatin structure [pompep4896]
  • |spt5||possibly involved in chromatin remodeling [pompepnew.fasta]
  • SPAC23C4.19 protein (Spt5 protein) [4896.FASTAC]
  • |spt5||involved in transcriptional regulation|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative involvement in chromatin structure [Schizosaccharomyces pombe]gi|2465160|emb|CAB16890.1| SPAC23C4.19 [Schizosaccharomyces pombe]gi|7493064|pir||T38274 probable transcription initiation protein - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |spt5||elongation factor Spt5p|Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O13936) Putative involvement in chromatin structure [pompep4896_normal_reversed]
  • |spt5||transcription elongation factor Spt5|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Transcription elongation factor spt5 (Chromatin elongation factor spt5) [nr-271106-contam.fasta]
  • hypothetical protein SPAC23C4.19 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC23C4.19 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Transcription elongation factor spt5 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spt5 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 990 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    DSIF complex [IDALink to PubMed article]
    Biological Process: negative regulation of RNA elongation from RNA polymerase II promoter [ISSLink to PubMed article]
    regulation of RNA elongation from RNA polymerase II promoter [TASLink to PubMed article]
    mRNA processing [IPILink to PubMed article]
    Molecular Function: RNA polymerase II transcription elongation factor activity [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTNSPKSID KDANSTEVDA AEQDAASVKI NSTRASPNGS DLLNDDSEAA KITTNEKQSS  60
   61 PVDSHNESPN DTTINKGEDG NENEVDNVNN NDKKEDEDNV EENEEEADAN EEEEEDEEDD 120
  121 EEDEEDEDES GGGRRKRARH DRRNQFLDIE AEVDEDEEEL EDEEDEIGRE DGFIEEEVGA 180
  181 DYVGDDRRHR ELDRQRQELQ SVDAERLAEE YREKYGRSQT VVGDTSNVPQ RLLLPSVNDP 240
  241 NIWAVRCKIG KEKDIVFTIM RKAMDLQYTS SPLEIISAFQ RDSLVGYIYV EARKQSHVLD 300
  301 ALNGVLNVYT NNMILVPIKE MPDLLKVQKQ VVELLPGAYV RIRRGKYAGD LAQVDNLSEN 360
  361 GLTARVRIVP RIDYSDGLKR KNSATRPQAR LFNESEAFKS NPSKFSKRGP RLFLFNNEEF 420
  421 EDGFLVKDIR ISSLITEGVN PTLDEVSKFN PNNEDLDLSS LALSVKGGHA EFQPGDHVEV 480
  481 YVGEQTGVSG VVENVRGSVI TMVSSDGLRL DVPSRGLRKR FRHGDYVKVI AGKYKDDTGM 540
  541 VVRISKDEVT FLSDTLMTEL TVFSRDLGEA SSAQAVNSAY ELHDLVQLDV NTVACIFSVD 600
  601 RDTYKVIDQN GGVRTVLASQ ITMRHSNRRG VATDRNGAEI RIGDKVKEVG GEGKQGTILH 660
  661 IYRAFVFLHN RDIAENNGVF SARSRNVATI AAKGARISAD LTKMNPALSN GPALPPVANL 720
  721 KRTIGRDKAI GATVRIRRGP MKGLLGVIKD TTDANARVEL HTGNKMVTIP KENLLYTTKT 780
  781 GELISYTEFI ERSRGIRPGS ISTADGPNVP NWAQGARTPA VANGSRTPAW NTGSRTPAWN 840
  841 SGSKTPAWNS GSRTPAWNSG NKTPAWNAGS RTPAWNSGNK TPAWNVGNKT PAWNSGAKTP 900
  901 AWNAGNKTPS WNNGTKTPAW NANQTPMVAN GTNTSWGQTP AYGGFSETNW DTEDNSKPYT 960
  961 APTPGAWAAP TPGGWDDEEG DSPKYVPPSP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] PSI-BLAST 3.69897 Tropomyosin
    2 View Details [184..377] PSI-BLAST 28.154902 No description for 2exuA was found.
    3 View Details [378..462] deduced N/A No confident structure predictions are available.
    4 View Details [463..507] FFAS03 2.47 No description for 2e6zA was found.
    5 View Details [508..578] PSI-BLAST 26.522879 No description for 2do3A was found.
    6 View Details [579..682] deduced N/A No confident structure predictions are available.
    7 View Details [683..990] PSI-BLAST 8.69897 No description for 1y0fA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle