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Protein Overview: SPBC119.03

General Information:
Name(s) found: SPBC119.03 [Sanger Pombe]
Description(s) found:
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  • pir||T39301 probable o-methyltransferase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74582133|sp|O42898.1|COMT1_SCHPO RecName: Full=Probable catechol O-methyltransferase 1 [NCBI NR]
  • gi|2959364|emb|CAA17918.1| human COMT homolog 1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112076|ref|NP_595284.1| S-adenosylmethionine-dependent methyltransferase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • S-adenosylmethionine-dependent methyltransferase [Sanger Pombe]
  • Probable catechol O-methyltransferase 1 OS=Schizosaccharomyces pombe GN=SPBC119.03 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE CATECHOL O-METHYLTRANSFERASE; NO APPARENT S. CEREVISIAE ORTHOLOG: O42898; [pompepVF.fasta]
  • PUTATIVE CATECHOL O-METHYLTRANSFERASE: O42898; [pompepV13]
  • Putative catechol o-methyltransferase [pompep4896]
  • |||putative catechol o-methyltransferase [pompepnew.fasta]
  • SPBC119.03 protein (EC 2.1.1.6) [4896.FASTAC]
  • |||S-adenosylmethionine-dependent methyltransferase activity (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • putative catechol o-methyltransferase [Schizosaccharomyces pombe]gi|2959364|emb|CAA17918.1| SPBC119.03 [Schizosaccharomyces pombe]gi|7492778|pir||T39301 probable o-methyltransferase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||S-adenosylmethionine-dependent methyltransferase activity |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (O42898) Putative catechol o-methyltransferase [pompep4896_normal_reversed]
  • |||human COMT homolog 1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • catechol O-methyltransferase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC119.03 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Probable catechol O-methyltransferase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC119.03 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 266 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: cellular response to stress [IEPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    catechol O-methyltransferase activity [IEA]
    O-methyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHMEDNGSE KEQLFLQHIQ NLPQERLDAI RGHPELVLKE IDEFTYPDGS GVRMCIGDVK  60
   61 GGFIVGKIRE RKPKIMVELG GYLGYSAILF GNEISKIPGG RYYSLEVNED YAKIAYELVK 120
  121 LAGLDEIVTI MIGKACDSLV ELQQKLLHKD LGFQALDMVF IDHWKDLYVP DLRVIESLNM 180
  181 IAPGTLLVAD NIITPGAPEY HKYVNMSPEE RRGYQAKVRN VNGFDFIGRW DLIYKTETKE 240
  241 FEGVIRNKHR KDAVDVTECV GYAKKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..266] PSI-BLAST 22.522879 Catechol O-methyltransferase, COMT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity
    		•  1.27257394278119 bayes_pls_golite062009
  • catalytic activity
    		•  0.486907672100804 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.155495931533276 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.145822362574272 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle