YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC119.03
Organism:	Schizosaccharomyces pombe
Length:	266 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC119.03.

Description	E-value	Query Range	Subject Range
gi\|50418623, gi\|... - gi\|50418623\|ref\|XP_457830.1\| hypothetical protein DEHA0C03916g [Debaryomyces hansenii CBS767], gi\|49...	154.0	[0..10]	[262..29]
gi\|46436802, gi\|... - gi\|77023174\|ref\|XP_889031.1\| hypothetical protein CaO19_7140 [Candida albicans SC5314], gi\|68481642\|... gi\|76573844 - gi\|76573844\|dbj\|BAE44928.1\| hypothetical protein [Candida albicans]	152.0	[0..10]	[262..2]
COMT2_SCHPO - Probable catechol O-methyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SP... SPBPB21E7.04c - S-adenosylmethionine-dependent methyltransferase	145.0	[0..5]	[261..29]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	136.0	[0..9]	[249..13]
gi\|47013898, gi\|... - gi\|47097727\|ref\|ZP_00235228.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyto... gi\|126943708, gi... - gi\|254899372\|ref\|ZP_05259296.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|127765209, gi... - gi\|254912489\|ref\|ZP_05262501.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|133732157, gi... - gi\|254936816\|ref\|ZP_05268513.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono...	135.0	[0..35]	[266..10]
UBIE_LISIN - Demethylmenaquinone methyltransferase OS=Listeria innocua GN=ubiE PE=3 SV=1 UBIE_LISMO - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes GN=ubiE PE=3 SV=1 MENG_LISIN - Demethylmenaquinone methyltransferase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=menG PE=... gi\|47094454, gi\|... - gi\|47094454\|ref\|ZP_00232134.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyto... UBIE_LISMC - Menaquinone biosynthesis methyltransferase ubiE OS=Listeria monocytogenes serotype 4b (strain Clip81... gi\|254825574 - gi\|254825574\|ref\|ZP_05230575.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254852834 - gi\|254852834\|ref\|ZP_05242182.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254877951 - gi\|254877951\|ref\|ZP_05250661.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... MENG_LISMC - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=me... MENG_LISMF - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=menG P... gi\|254993470 - gi\|254993470\|ref\|ZP_05275660.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... MENG_LISMO - Demethylmenaquinone methyltransferase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / ... gi\|255521039 - gi\|255521039\|ref\|ZP_05388276.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|254831468, gi... - gi\|254831468\|ref\|ZP_05236123.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|153167788, gi... - gi\|153167788\|ref\|ZP_01927873.1\| 2-heptaprenyl-1,4-naphthoquinone methyltransferase [Listeria monocyt... gi\|254827184, gi... - gi\|254827184\|ref\|ZP_05231871.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|153202924, gi... - gi\|254931898\|ref\|ZP_05265257.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|224498619 - gi\|224498619\|ref\|ZP_03666968.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono... gi\|224501270 - gi\|224501270\|ref\|ZP_03669577.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Listeria mono...	135.0	[0..35]	[266..10]
gi\|218321183, gi... - gi\|218708164\|ref\|YP_002415785.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splen... gi\|85835662, gi\|... - gi\|86146605\|ref\|ZP_01064927.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio sp. MED...	135.0	[0..1]	[249..7]
gi\|84386296, gi\|... - gi\|84386296\|ref\|ZP_00989324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splendi...	134.0	[0..1]	[249..7]
gi\|194537307, gi... - gi\|75820016\|ref\|ZP_00750074.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...	134.0	[0..9]	[249..13]
UBIE_HAHCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Hahella chejuensis (strain KCTC 2396...	133.0	[0..10]	[207..3]

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Predicted Domain #1

Region A:
Residues: [1-266]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHMEDNGSE KEQLFLQHIQ NLPQERLDAI RGHPELVLKE IDEFTYPDGS GVRMCIGDVK  60
   61 GGFIVGKIRE RKPKIMVELG GYLGYSAILF GNEISKIPGG RYYSLEVNED YAKIAYELVK 120
  121 LAGLDEIVTI MIGKACDSLV ELQQKLLHKD LGFQALDMVF IDHWKDLYVP DLRVIESLNM 180
  181 IAPGTLLVAD NIITPGAPEY HKYVNMSPEE RRGYQAKVRN VNGFDFIGRW DLIYKTETKE 240
  241 FEGVIRNKHR KDAVDVTECV GYAKKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.522879
Match:	1h1dA
Description:	Catechol O-methyltransferase, COMT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	1.27257394278119	bayes_pls_golite062009
catalytic activity	0.486907672100804	bayes_pls_golite062009
methyltransferase activity	0.155495931533276	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.145822362574272	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: