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Protein Overview: SPBC3D6.03c

General Information:
Name(s) found: SPBC3D6.03c [Sanger Pombe]
Description(s) found:
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  • pir||T40362 conserved hypothetical protein SPBC3D6.03c - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74644192|sp|P87168.1|RNZ2_SCHPO RecName: Full=Probable ribonuclease Z 2; Short=RNase Z 2; AltName: Full=tRNase Z 2; AltName: Full=tRNA 3 endonuclease 2 [NCBI NR]
  • gi|2117299|emb|CAB09123.1| tRNA endonuclease Trz1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112306|ref|NP_595514.1| tRNA endonuclease (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • tRNA endonuclease [Sanger Pombe]
  • Probable ribonuclease Z 2 OS=Schizosaccharomyces pombe GN=SPBC3D6.03c PE=2 SV=1 [Swiss-Prot]
  • METALLO-BETA-LACTAMASE FAMILY PROTEIN; CONSERVED IN EUKARYOTES: P87168; [pompepVF.fasta]
  • METALLO-BETA-LACTAMASE SUPERFAMILY PROTEIN; CONSERVED IN EUKARYOTES: P87168; [pompepV13]
  • Metallo-beta-lactamase family protein, conserved in eukaryotes [pompep4896]
  • |||Metallo-beta-lactamase family protein [pompepnew.fasta]
  • SPBC3D6.03c protein [4896.FASTAC]
  • |||ribonuclease (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • conserved hypothetical protein [Schizosaccharomyces pombe]gi|7490345|pir||T40362 conserved hypothetical protein SPBC3D6.03c - fission yeast (Schizosaccharomyces pombe)gi|2117299|emb|CAB09123.1| ribonuclease (predicted); predicted N-terminal signal sequ [nrdb_11152004_Chlamydomonas]
  • |||ribonuclease|Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (P87168) Metallo-beta-lactamase family protein, conserved in eukaryotes [pompep4896_normal_reversed]
  • |trzl|sptrz1|tRNA endonuclease Trz1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC3D6.03c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • ribonuclease [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • |||tRNA endonuclease |Schizosaccharomyces pombe|chr 2|||Manual [spombe-190209-contam.fasta]
  • |trz2|sptrz2|mitochondrial 3'-tRNA processing endonuclease Trz2|Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Ribonuclease Z 2, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=trz2 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 678 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: tRNA 3'-trailer cleavage [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    3'-tRNA processing endoribonuclease activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASLLVPRR ALLFGQLLPP KYSWYSVKRW QSQLTFRNKS KRNTNRIMLS VVSSLNPDSL  60
   61 IAPLLCVSLD NRKYLIGSMG ELTQMKFRSQ ASNYGGKSVS VFLMPPSLQS LNAWGITAGL 120
  121 FGYLQSSGIQ NTWGLHAPKP VISIIKKSHH LFSGSPLRLD LNSFSSEDNA DATNSFYLDE 180
  181 PEFCTIKGNI YSNWSFLSFN SKEAAGVFNA DKALALGVPF GPSNGKLCAG EAVLSKDGTT 240
  241 WIYPHQVVGP PRKRQYFYVL GCSSLSALNQ MSKHVDSFSD VYPTCIIHIL EKGIWGPEYI 300
  301 KFLSHPKFSR AQHFISCIEL ASNNPVFQRN KGRNVLPACR DFAAFDIKPS TLDTQTQLPE 360
  361 NTYVLKEETS MVLYDEQCKI SESPSYSPVK LAKKFSSFNP LPFENEGYTL DVLGTSATCP 420
  421 TWRRSLSSYS VAIDGTVIML DCGEGAISQF FRQYGTNTEP MLRKLKAIFI THLHSDHYLG 480
  481 LLNVLQAWNK ANTNNSMHIN IIGPKFLWQW LQRLKSPANL QALLNRIIFI IAKETVTTPL 540
  541 QLTSDLSISS VPSIHINDSY SCIISHTKYG KLVYSGDTRP NEKLVKAGIG ASLLLHESTF 600
  601 EDDLKHEAIQ RQHSTASEAL SVAQSMKAKA LILTHFSQRS YDADFLPPDW TIYPKSKTIY 660
  661 ANDGLQWQQF QSKQRETI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..354] PSI-BLAST 67.69897 Crystal structure of RNase Z
    2 View Details [355..678] PSI-BLAST 34.69897 1.5A Resolution Crystal Structure of a Metallo Beta Lactamase Family Protein, the ELAC Homolgue of Bacillus anthracis, a Putative Ribonuclease

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3'-tRNA processing endoribonuclease activity
    		•  0.998280249151351 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.980281910076056 bayes_pls_golite062009
  • catalytic activity
    		•  0.941400907161877 bayes_pls_golite062009
  • binding
    		•  0.862029507899862 bayes_pls_golite062009
  • RNA binding
    		•  0.794779546418275 bayes_pls_golite062009
    2
    Term Confidence Notes
  • 3'-tRNA processing endoribonuclease activity
    		•  0.998280249151351 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.980281910076056 bayes_pls_golite062009
  • catalytic activity
    		•  0.941400907161877 bayes_pls_golite062009
  • binding
    		•  0.862029507899862 bayes_pls_golite062009
  • RNA binding
    		•  0.794779546418275 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle