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View Structure Prediction Details

Protein: SPBC3D6.03c
Organism: Schizosaccharomyces pombe
Length: 678 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC3D6.03c.

Description E-value Query
Range
Subject
Range
RNZ2_MACFA - Zinc phosphodiesterase ELAC protein 2 OS=Macaca fascicularis GN=ELAC2 PE=2 SV=1
344.0 [0..17] [676..33]
RNZ2_PANTR - Zinc phosphodiesterase ELAC protein 2 OS=Pan troglodytes GN=ELAC2 PE=2 SV=1
341.0 [0..29] [669..38]
ELAC2 - elaC homolog 2 (E. coli)
341.0 [0..29] [669..38]
RNZ2_GORGO - Zinc phosphodiesterase ELAC protein 2 OS=Gorilla gorilla gorilla GN=ELAC2 PE=2 SV=1
gi|10946489 - gi|10946489|gb|AAG24916.1|AF308694_1 ELAC2 [Gorilla gorilla]
340.0 [0..29] [669..38]
gi|108873466, gi... - gi|157125937|ref|XP_001654456.1| zinc phosphodiesterase [Aedes aegypti], gi|108873466|gb|EAT37691.1|...
336.0 [0..16] [672..1]
gi|25405531, gi|... - gi|6850339|gb|AAF29402.1|AC022354_1 unknown protein [Arabidopsis thaliana], pir||F96561 unknown prot...
329.0 [0..23] [667..16]

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Predicted Domain #1
Region A:
Residues: [1-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKASLLVPRR ALLFGQLLPP KYSWYSVKRW QSQLTFRNKS KRNTNRIMLS VVSSLNPDSL  60
   61 IAPLLCVSLD NRKYLIGSMG ELTQMKFRSQ ASNYGGKSVS VFLMPPSLQS LNAWGITAGL 120
  121 FGYLQSSGIQ NTWGLHAPKP VISIIKKSHH LFSGSPLRLD LNSFSSEDNA DATNSFYLDE 180
  181 PEFCTIKGNI YSNWSFLSFN SKEAAGVFNA DKALALGVPF GPSNGKLCAG EAVLSKDGTT 240
  241 WIYPHQVVGP PRKRQYFYVL GCSSLSALNQ MSKHVDSFSD VYPTCIIHIL EKGIWGPEYI 300
  301 KFLSHPKFSR AQHFISCIEL ASNNPVFQRN KGRNVLPACR DFAAFDIKPS TLDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.69897
Match: 1y44A
Description: Crystal structure of RNase Z
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
3'-tRNA processing endoribonuclease activity 0.998280249151351 bayes_pls_golite062009
nucleic acid binding 0.980281910076056 bayes_pls_golite062009
catalytic activity 0.941400907161877 bayes_pls_golite062009
binding 0.862029507899862 bayes_pls_golite062009
RNA binding 0.794779546418275 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [355-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTQLPENTYV LKEETSMVLY DEQCKISESP SYSPVKLAKK FSSFNPLPFE NEGYTLDVLG  60
   61 TSATCPTWRR SLSSYSVAID GTVIMLDCGE GAISQFFRQY GTNTEPMLRK LKAIFITHLH 120
  121 SDHYLGLLNV LQAWNKANTN NSMHINIIGP KFLWQWLQRL KSPANLQALL NRIIFIIAKE 180
  181 TVTTPLQLTS DLSISSVPSI HINDSYSCII SHTKYGKLVY SGDTRPNEKL VKAGIGASLL 240
  241 LHESTFEDDL KHEAIQRQHS TASEALSVAQ SMKAKALILT HFSQRSYDAD FLPPDWTIYP 300
  301 KSKTIYANDG LQWQQFQSKQ RETI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.69897
Match: 1zkpA
Description: 1.5A Resolution Crystal Structure of a Metallo Beta Lactamase Family Protein, the ELAC Homolgue of Bacillus anthracis, a Putative Ribonuclease
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
3'-tRNA processing endoribonuclease activity 0.998280249151351 bayes_pls_golite062009
nucleic acid binding 0.980281910076056 bayes_pls_golite062009
catalytic activity 0.941400907161877 bayes_pls_golite062009
binding 0.862029507899862 bayes_pls_golite062009
RNA binding 0.794779546418275 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle