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Protein Overview: ain1

General Information:
Name(s) found: ain1 / SPAC15A10.08 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • alpha-actinin [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 621 amino acids

    Gene Ontology:
    Cellular Component: actomyosin contractile ring [IDALink to PubMed article]
    Biological Process: actin crosslink formation [TASLink to PubMed article]
    cytokinesis, actomyosin contractile ring assembly [IMPLink to PubMed article]
    actin cytoskeleton organization [IMPLink to PubMed article]
    actin filament bundle assembly [TASLink to PubMed article]
    Molecular Function: actin binding [TASLink to PubMed article]
    calcium ion binding [IEA]
    protein binding, bridging [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQANQWQSVQ NRTFTKWFNT KLSSRDLPSV FDLRKDLSDG ILLIQLLEII GDENLGRYNR  60
   61 NPRMRVHRLE NVNKALEYIK SKGMPLTNIG PADIVDGNLK LILGLIWTLI LRFTIADINE 120
  121 EGLTAKEGLL LWCQRKTANY HPEVDVQDFT RSWTNGLAFC ALIHQHRPDL LDYNKLDKKN 180
  181 HRANMQLAFD IAQKSIGIPR LIEVEDVCDV DRPDERSIMT YVAEYFHAFS TLDKVETAAR 240
  241 RVERFTEVLM STHDMKIDYE SRMKRLLGSI ARMQEYWHTV QFENNYTDVK SHSNNFAKFK 300
  301 ATEKREWVKE KIDLESLLGT IQTNLKTYQL RKYEPPAGLK IVDLERQWKD FLSEEANQSK 360
  361 LINTHMREIK ESMRIAFADR ANSFSKMLST ISNEITNLQG DWRDQLDHVE FLQEHLGPLE 420
  421 VELASVKVLY DNCFQAGIEE NDYTMFSYED LEHEFGITAN IIANKIKYLE NELLEREKRT 480
  481 LSKQELDGIT KVFRHFEKKK SNMLNEVEFY AALASLGLVY DTEEGTALFH RAANSEEGVT 540
  541 YERFTEIVME ELEDRDSARQ VLYAFCDVAD GKSYVTSDDL LRSQVRPNIV KFLECNMNKH 600
  601 SEGLDYLTWI KQLLAEDKEI V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..535] PSI-BLAST 114.0 Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin
    2 View Details [536..621] PSI-BLAST 31.0 Trapped intermediate of calmodulin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • actin binding
    		•  3.96919556235483 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.49668552859347 bayes_pls_golite062009
  • structural constituent of muscle
    		•  3.12414907235012 bayes_pls_golite062009
  • microfilament motor activity
    		•  2.9702957313812 bayes_pls_golite062009
  • binding
    		•  2.59835122922082 bayes_pls_golite062009
  • motor activity
    		•  2.57627414053278 bayes_pls_golite062009
  • actin filament binding
    		•  2.35534489389161 bayes_pls_golite062009
  • myosin binding
    		•  2.34125070430971 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.06646671333275 bayes_pls_golite062009
  • calcium ion binding
    		•  1.85627588382967 bayes_pls_golite062009
  • protein binding
    		•  1.36984860219682 bayes_pls_golite062009
  • cation binding
    		•  1.19984728454368 bayes_pls_golite062009
  • metal ion binding
    		•  1.19984728454368 bayes_pls_golite062009
  • ion binding
    		•  1.1923653453763 bayes_pls_golite062009
  • actin monomer binding
    		•  0.9954841049256 bayes_pls_golite062009
  • tubulin binding
    		•  0.710693016758742 bayes_pls_golite062009
  • myosin heavy chain binding
    		•  0.61866037435065 bayes_pls_golite062009
  • myosin II binding
    		•  0.311147527050891 bayes_pls_golite062009
  • microtubule binding
    		•  0.278596514315141 bayes_pls_golite062009
  • structural molecule activity
    		•  0.234626449126289 bayes_pls_golite062009
  • myosin II heavy chain binding
    		•  0.197999145365609 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.116648335890738 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle