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View Structure Prediction Details

Protein: ain1
Organism: Schizosaccharomyces pombe
Length: 621 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ain1.

Description E-value Query
Range
Subject
Range
gi|32411607, gi|... - gi|32411607|ref|XP_326284.1| hypothetical protein [Neurospora crassa], gi|28918410|gb|EAA28084.1| hy...
gi|85084500 - gi|85084500|ref|XP_957320.1| hypothetical protein NCU06429 [Neurospora crassa OR74A]
456.0 [0..2] [618..315]
gi|76668414 - gi|76668414|ref|XP_604386.2| PREDICTED: similar to Spectrin beta chain, brain 1 (Spectrin, non-eryth...
444.0 [0..1] [579..112]
gi|39977145, gi|... - gi|39977145|ref|XP_369960.1| hypothetical protein MG06475.4 [Magnaporthe grisea 70-15], gb|EAA56504....
430.0 [0..3] [617..149]
gi|42554674, gi|... - gi|46125813|ref|XP_387460.1| hypothetical protein FG07284.1 [Gibberella zeae PH-1], gi|42554674|gb|E...
428.0 [0..2] [617..240]
gi|90301705, gi|... - gi|90301705|gb|EAS31336.1| conserved hypothetical protein [Coccidioides immitis RS], gi|119183879|re...
424.0 [0..3] [615..5]
gi|46100341, gi|... - gi|71020457|ref|XP_760459.1| hypothetical protein UM04312.1 [Ustilago maydis 521], ref|XP_401927.1| ...
424.0 [0..2] [618..15]
gi|73963343 - gi|73963343|ref|XP_866895.1| PREDICTED: similar to Alpha-actinin 1 (Alpha-actinin cytoskeletal isofo...
418.0 [0..1] [513..24]
gi|41054603, gi|... - gi|41054603|ref|NP_955880.1| actinin alpha 4 [Danio rerio], gi|32766291|gb|AAH54901.1| Actinin, alph...
415.0 [0..1] [540..33]
gi|38018016 - gi|38018016|gb|AAR08137.1| brain-specific alpha actinin 1 isoform [Rattus norvegicus]
414.0 [0..1] [513..24]

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Predicted Domain #1
Region A:
Residues: [1-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQANQWQSVQ NRTFTKWFNT KLSSRDLPSV FDLRKDLSDG ILLIQLLEII GDENLGRYNR  60
   61 NPRMRVHRLE NVNKALEYIK SKGMPLTNIG PADIVDGNLK LILGLIWTLI LRFTIADINE 120
  121 EGLTAKEGLL LWCQRKTANY HPEVDVQDFT RSWTNGLAFC ALIHQHRPDL LDYNKLDKKN 180
  181 HRANMQLAFD IAQKSIGIPR LIEVEDVCDV DRPDERSIMT YVAEYFHAFS TLDKVETAAR 240
  241 RVERFTEVLM STHDMKIDYE SRMKRLLGSI ARMQEYWHTV QFENNYTDVK SHSNNFAKFK 300
  301 ATEKREWVKE KIDLESLLGT IQTNLKTYQL RKYEPPAGLK IVDLERQWKD FLSEEANQSK 360
  361 LINTHMREIK ESMRIAFADR ANSFSKMLST ISNEITNLQG DWRDQLDHVE FLQEHLGPLE 420
  421 VELASVKVLY DNCFQAGIEE NDYTMFSYED LEHEFGITAN IIANKIKYLE NELLEREKRT 480
  481 LSKQELDGIT KVFRHFEKKK SNMLNEVEFY AALASLGLVY DTEEGTALFH RAANS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1sjjA
Description: Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [536-621]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEGVTYERFT EIVMEELEDR DSARQVLYAF CDVADGKSYV TSDDLLRSQV RPNIVKFLEC  60
   61 NMNKHSEGLD YLTWIKQLLA EDKEIV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1y6wA
Description: Trapped intermediate of calmodulin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.96919556235483 bayes_pls_golite062009
cytoskeletal protein binding 3.49668552859347 bayes_pls_golite062009
structural constituent of muscle 3.12414907235012 bayes_pls_golite062009
microfilament motor activity 2.9702957313812 bayes_pls_golite062009
binding 2.59835122922082 bayes_pls_golite062009
motor activity 2.57627414053278 bayes_pls_golite062009
actin filament binding 2.35534489389161 bayes_pls_golite062009
myosin binding 2.34125070430971 bayes_pls_golite062009
actin-dependent ATPase activity 2.06646671333275 bayes_pls_golite062009
calcium ion binding 1.85627588382967 bayes_pls_golite062009
protein binding 1.36984860219682 bayes_pls_golite062009
cation binding 1.19984728454368 bayes_pls_golite062009
metal ion binding 1.19984728454368 bayes_pls_golite062009
ion binding 1.1923653453763 bayes_pls_golite062009
actin monomer binding 0.9954841049256 bayes_pls_golite062009
tubulin binding 0.710693016758742 bayes_pls_golite062009
myosin heavy chain binding 0.61866037435065 bayes_pls_golite062009
myosin II binding 0.311147527050891 bayes_pls_golite062009
microtubule binding 0.278596514315141 bayes_pls_golite062009
structural molecule activity 0.234626449126289 bayes_pls_golite062009
myosin II heavy chain binding 0.197999145365609 bayes_pls_golite062009
structural constituent of cytoskeleton 0.116648335890738 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle