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Protein Overview: SPAC11E3.11c

General Information:
Name(s) found: SPAC11E3.11c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • guanyl-nucleotide exchange factor [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 942 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: vesicle-mediated transport [ISSLink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    regulation of ARF protein signal transduction [IEA]
    intracellular protein transport [ISSLink to PubMed article]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IEA]
    guanyl-nucleotide exchange factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRNASNAYL KNGNSTPSND KRSPSSLSQR SKTSTRSSKP FLQRLFPSTW FKNESSSRHP  60
   61 LTSIKENDTQ TIGRRPSMRV KLFGKDKSKA SMSTNDLPSH PRSQSVMGFS SSTSQLTGTS 120
  121 NSSRTRLNKD MRRDFGMTSM SSITSSTPTP SQLPVRPSTS LSFFDDIPLG PSFSAETILS 180
  181 SLSISTSNNA MSKTTPAPPL VTTKSISADQ DDFYTCKEEV STYEGLNSQI ELSPVKSRDS 240
  241 QNKSAKNLST AYRTVSGESR NLMVDPKVSP YGNSRTPLRD SSNYLRDRRS INRQSSLSIP 300
  301 KSTSETTRKT LALSNGGIDQ SRVSSDSFKV DDSSAKMAAI DIWEGSQHIV SNDKALSWLV 360
  361 TDKPYNKAVL KHYISLYDFE NTDILQSLRM ICGNLYVHGE TQELDHFLGE FSNQWCRTNP 420
  421 KGLFCNPQIV HSIAFSLLLL NTDLHIAELS ASERMSRNQF VENTYRSIKQ ALNDSFDGNE 480
  481 EKKNAFFLSS YKSFASNESC NSPAIHSLHG NLSPGKSAEL KKLHKRSLSS KVLEEAFSSY 540
  541 WMSALKEMYH SIKVSMILQP DRYLDMNFDF NDTNKINNPS STANQTRHFH SVSEIKKLPM 600
  601 GTDELEKSMV RPSTAMYINR QNENAVSIDK SRDLQGTVNT KEIRSRSALS YQNDRPLATD 660
  661 LPSVIYNHKH PNVVSPFYVH PYIKQGILKF QSKESHKFRK KEVWSTVLAV LQRDVFTLYN 720
  721 LNTPNLSYDP KDLDISKVGK PVIKTTIIAS LAKPFPSSED AVVLKSTNSL YFDLETSSQL 780
  781 KLRFAGPSPK DAQGWIDALN YWAARSSKVP LLGGVTNVDY GWARCTGQRA QKSNAQLLKT 840
  841 KTDKIIVHKW QPQPVNTIPS SLSLGEQLSA FNNFMKLLKK TNDEHQNLHK EMLVVLSSQP 900
  901 KSTFRRAVEN WKYKSDYLQL NLVRLRVYIS VLEKYKSQAQ NS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..224] MSA 10.325996 View MSA. No confident structure predictions are available.
    2 View Details [225..296] deduced N/A No confident structure predictions are available.
    3 View Details [297..623] PSI-BLAST 61.0 The structure of RalF
    4 View Details [624..807] PSI-BLAST 18.69897 NMR STRUCTURE OF THE CYTOSKELETON/SIGNAL TRANSDUCTION PROTEIN
    5 View Details [808..942] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • ARF guanyl-nucleotide exchange factor activity
    		•  2.85107511747528 bayes_pls_golite062009
  • GTPase regulator activity
    		•  2.5558921150723 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.54940908113844 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  2.37585942052733 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  2.14471582456507 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.68310328476502 bayes_pls_golite062009
  • protein binding
    		•  0.852753661953164 bayes_pls_golite062009
  • binding
    		•  0.559114322046591 bayes_pls_golite062009
    4
    Term Confidence Notes
  • protein binding
    		•  2.26451794172088 bayes_pls_golite062009
  • binding
    		•  1.93922754478502 bayes_pls_golite062009
  • phospholipid binding
    		•  0.107467402828628 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle