YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC11E3.11c
Organism:	Schizosaccharomyces pombe
Length:	942 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC11E3.11c.

Description	E-value	Query Range	Subject Range
gi\|42553344, gi\|... - gi\|46125229\|ref\|XP_387168.1\| hypothetical protein FG06992.1 [Gibberella zeae PH-1], gi\|42553344\|gb\|E...	559.0	[0..2]	[940..408]
gi\|49092228, gi\|... - gi\|67525961\|ref\|XP_661042.1\| hypothetical protein AN3438.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	435.0	[0..8]	[939..343]
gi\|27803074, gi\|... - gi\|27803074\|emb\|CAD60777.1\| unnamed protein product [Podospora anserina], gi\|188219317\|emb\|CAP49297.... gi\|189091928 - gi\|189091928\|ref\|XP_001929797.1\| [Podospora anserina]	426.0	[0..28]	[841..437]
gi\|39973851, gi\|... - gi\|39973851\|ref\|XP_368316.1\| hypothetical protein MG00928.4 [Magnaporthe grisea 70-15], gb\|EAA49270....	409.0	[0..3]	[839..329]
gi\|114189397, gi... - gi\|115402949\|ref\|XP_001217551.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	407.0	[0..2]	[940..350]
gi\|40804593, gi\|... - gi\|40804593\|emb\|CAF05854.1\| conserved hypothetical protein [Neurospora crassa], gi\|32421359\|ref\|XP_3... gi\|85092586 - gi\|85092586\|ref\|XP_959469.1\| hypothetical protein NCU11254 [Neurospora crassa OR74A]	404.0	[0..28]	[837..450]
gi\|169779910 - gi\|169779910\|ref\|XP_001824419.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83773159 - gi\|83773159\|dbj\|BAE63286.1\| unnamed protein product [Aspergillus oryzae]	401.0	[0..8]	[939..390]
gi\|119195363, gi... - gi\|90307071\|gb\|EAS36702.1\| hypothetical protein CIMG_02056 [Coccidioides immitis RS], gi\|119195363\|r...	401.0	[0..9]	[940..374]
gi\|71004066, gi\|... - gi\|71004066\|ref\|XP_756699.1\| hypothetical protein UM00552.1 [Ustilago maydis 521], ref\|XP_398167.1\| ...	392.0	[0..1]	[935..590]
gi\|71000701, gi\|... - gi\|71000701\|ref\|XP_755032.1\| Sec7 domain protein [Aspergillus fumigatus Af293], gi\|66852669\|gb\|EAL92...	392.0	[0..13]	[939..397]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRNASNAYL KNGNSTPSND KRSPSSLSQR SKTSTRSSKP FLQRLFPSTW FKNESSSRHP  60
   61 LTSIKENDTQ TIGRRPSMRV KLFGKDKSKA SMSTNDLPSH PRSQSVMGFS SSTSQLTGTS 120
  121 NSSRTRLNKD MRRDFGMTSM SSITSSTPTP SQLPVRPSTS LSFFDDIPLG PSFSAETILS 180
  181 SLSISTSNNA MSKTTPAPPL VTTKSISADQ DDFYTCKEEV STYE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [225-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLNSQIELSP VKSRDSQNKS AKNLSTAYRT VSGESRNLMV DPKVSPYGNS RTPLRDSSNY  60
   61 LRDRRSINRQ SS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [297-623]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSIPKSTSET TRKTLALSNG GIDQSRVSSD SFKVDDSSAK MAAIDIWEGS QHIVSNDKAL  60
   61 SWLVTDKPYN KAVLKHYISL YDFENTDILQ SLRMICGNLY VHGETQELDH FLGEFSNQWC 120
  121 RTNPKGLFCN PQIVHSIAFS LLLLNTDLHI AELSASERMS RNQFVENTYR SIKQALNDSF 180
  181 DGNEEKKNAF FLSSYKSFAS NESCNSPAIH SLHGNLSPGK SAELKKLHKR SLSSKVLEEA 240
  241 FSSYWMSALK EMYHSIKVSM ILQPDRYLDM NFDFNDTNKI NNPSSTANQT RHFHSVSEIK 300
  301 KLPMGTDELE KSMVRPSTAM YINRQNE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.0
Match:	1xszA
Description:	The structure of RalF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ARF guanyl-nucleotide exchange factor activity	2.85107511747528	bayes_pls_golite062009
GTPase regulator activity	2.5558921150723	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	2.54940908113844	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	2.37585942052733	bayes_pls_golite062009
small GTPase regulator activity	2.14471582456507	bayes_pls_golite062009
enzyme regulator activity	1.68310328476502	bayes_pls_golite062009
protein binding	0.852753661953164	bayes_pls_golite062009
binding	0.559114322046591	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [624-807]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAVSIDKSRD LQGTVNTKEI RSRSALSYQN DRPLATDLPS VIYNHKHPNV VSPFYVHPYI  60
   61 KQGILKFQSK ESHKFRKKEV WSTVLAVLQR DVFTLYNLNT PNLSYDPKDL DISKVGKPVI 120
  121 KTTIIASLAK PFPSSEDAVV LKSTNSLYFD LETSSQLKLR FAGPSPKDAQ GWIDALNYWA 180
  181 ARSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.69897
Match:	1droA
Description:	NMR STRUCTURE OF THE CYTOSKELETON/SIGNAL TRANSDUCTION PROTEIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	2.26451794172088	bayes_pls_golite062009
binding	1.93922754478502	bayes_pls_golite062009
phospholipid binding	0.107467402828628	bayes_pls_golite062009

Predicted Domain #5

Region A:
Residues: [808-942]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVPLLGGVTN VDYGWARCTG QRAQKSNAQL LKTKTDKIIV HKWQPQPVNT IPSSLSLGEQ  60
   61 LSAFNNFMKL LKKTNDEHQN LHKEMLVVLS SQPKSTFRRA VENWKYKSDY LQLNLVRLRV 120
  121 YISVLEKYKS QAQNS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.811	0.253	vesicle-mediated transport	a.47.2	t-snare proteins

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: