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Protein Overview: SPCC1450.10c

General Information:
Name(s) found: SPCC1450.10c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • iron hydrogenase large subunit [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 538 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: iron-sulfur cluster assembly [ISSLink to PubMed article]
    Molecular Function: ferredoxin hydrogenase activity [ISSLink to PubMed article]
    iron ion binding [IEA]
    4 iron, 4 sulfur cluster binding [IEA]
    iron-sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKLSVNDLN DFLSPGAVCI KPAQVKKQES KNDIRIDGDA YYEVTKDTGE TSELGIASIS  60
   61 LNDCLACSGC ITSAETVLVN LQSYQEVLKH LESRKSQEIL YVSLSPQVRA NLAAYYGLSL 120
  121 QEIQAVLEMV FIGKLGFHAI LDTNASREIV LQQCAQEFCN SWLQSRAHKN QNQVTNSVVN 180
  181 EHPLIPHSTS QISGVHSNTS SNSGINENAV LPILSSSCPG WICYVEKTHS NLIPNLSRVR 240
  241 SPQQACGRIL KDWAVQQFSM QRNDVWHLSL MPCFDKKLEA SRDEFSENGV RDVDSVLTPK 300
  301 ELVEMFKFLR IDPIELTKNP IPFQQSTDAI PFWYPRITYE EQIGSSSGGY MGYVLSYAAK 360
  361 MLFGIDDVGP YVSMNNKNGD LTEYTLRHPE TNEQLISMAT CYGFRNIQNL VRRVHGNSSV 420
  421 RKGRVLLKKR VRSNAQNPTE EPSRYDYVEV MACPGGCING GGQLPFPSVE RIVSARDWMQ 480
  481 QVEKLYYEPG TRSVDQSAVS YMLEQWVKDP TLTPKFLHTS YRAVQTDNDN PLLLANKW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..538] PSI-BLAST 118.0 Fe-only hydrogenase, catalytic domain; Fe-only hydrogenase, N-terminal domain; Fe-only hydrogenase, second domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.47874003627413 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  1.31458462821219 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.18054918348653 bayes_pls_golite062009
  • metal cluster binding
    		•  1.18054918348653 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  1.10428419414285 bayes_pls_golite062009
  • lamin binding
    		•  0.863386378061341 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  0.778342926116907 bayes_pls_golite062009
  • catalytic activity
    		•  0.488483980994331 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  0.312816353615077 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  0.278768281741128 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  0.278768281741128 bayes_pls_golite062009
  • protein binding
    		•  0.221871950373022 bayes_pls_golite062009
  • electron carrier activity
    		•  0.0554226204149908 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle