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Protein Overview: yak3

General Information:
Name(s) found: yak3 / SPAC1F7.12 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • aldose reductase YakC [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 340 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: cellular response to stress [IEPLink to PubMed article]
    Molecular Function: oxidoreductase activity, acting on CH-OH group of donors [IDALink to PubMed article]
    [NOT]pyridoxal 4-dehydrogenase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIPTRKIGN DTVPAIGFGC MGLHAMYGPS SEEANQAVLT HAADLGCTFW DSSDMYGFGA  60
   61 NEECIGRWFK QTGRRKEIFL ATKFGYEKNP ETGELSLNNE PDYIEKALDL SLKRLGIDCI 120
  121 DLYYVHRFSG ETPIEKIMGA LKKCVEAGKI RYIGLSECSA NTIRRAAAVY PVSAVQVEYS 180
  181 PFSLEIERPE IGVMKACREN NITIVCYAPL GRGFLTGAYK SPDDFPEGDF RRKAPRYQKE 240
  241 NFYKNLELVT KIEKIATANN ITPGQLSLAW LLAQGDDILP IPGTKRVKYL EENFGALKVK 300
  301 LSDATVKEIR EACDNAEVIG ARYPPGAGSK IFMDTPPMPK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..340] PSI-BLAST 81.522879 Structure of NADPH-dependent family 11 aldo-keto reductase AKR11B(holo)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pyridoxine 4-dehydrogenase activity
    		•  3.25535446462297 bayes_pls_golite062009
  • aldo-keto reductase activity
    		•  2.57303336304449 bayes_pls_golite062009
  • aryl-alcohol dehydrogenase activity
    		•  2.5168190536972 bayes_pls_golite062009
  • catalytic activity
    		•  1.68179794468736 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.48881830724998 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47641884930911 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.17915737521094 bayes_pls_golite062009
  • aldehyde reductase activity
    		•  1.16639404121425 bayes_pls_golite062009
  • binding
    		•  1.15657176144267 bayes_pls_golite062009
  • protein binding
    		•  0.220529867719707 bayes_pls_golite062009
  • 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity
    		•  0.207008954325429 bayes_pls_golite062009
  • trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
    		•  0.207008954325429 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.56

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle