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Protein Overview: atg22

General Information:
Name(s) found: atg22 / SPAC2G11.13 [Sanger Pombe]
Description(s) found:
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  • pir||S62468 probable membrane transporter - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19114005|ref|NP_593093.1| autophagy associated protein Atg22 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1175485|sp|Q09812.1|ATG22_SCHPO RecName: Full=Autophagy-related protein 22 [NCBI NR]
  • gi|1019411|emb|CAA91178.1| vacuolar amino acid efflux transporter Atg22 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • autophagy associated protein Atg22 [Sanger Pombe]
  • (Q09812) Hypothetical protein C2G11.13 in chromosome I [Swiss-Prot]
  • Autophagy-related protein 22 OS=Schizosaccharomyces pombe GN=atg22 PE=2 SV=1 [Swiss-Prot]
  • MFS TRANSPORTER OF UNKNOWN SPECIFICITY: Q09812; [pompepVF.fasta]
  • Hypothetical protein C2G11.13 in chromosome I [pompep4896]
  • |||MFS transporter of unknown specificity [pompepnew.fasta]
  • |||hypothetical protein|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • similarity to bacterial membrane transporter [Schizosaccharomyces pombe]gi|1019411|emb|CAA91178.1| SPAC2G11.13 [Schizosaccharomyces pombe]gi|1175485|sp|Q09812|YABD_SCHPO Hypothetical protein C2G11.13 in chromosome Igi|2130398|pir||S62468 probable membr [nrdb_11152004_Chlamydomonas]
  • |atg22||vacuolar amino acid efflux transporter Atg22 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC2G11.13 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC2G11.13 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Autophagy-related protein 22 [nr-271106-contam.fasta]
  • |atg22||vacuolar amino acid efflux transporter Atg22|Schizosaccharomyces pombe|chr 1|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Autophagy-related protein 22 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atg22 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 529 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole membrane [IDALink to PubMed article][ISSLink to PubMed article]
    integral to membrane [IEA]
    Biological Process: [NOT]autophagy [IMPLink to PubMed article]
    amino acid export from vacuole [ISS]
    cellular response to nitrogen starvation [IMPLink to PubMed article]
    Molecular Function: L-amino acid efflux transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSPIQLHKK FSTTVWHVLS WILYAVGAGP TAIISMGVYV PLIVMKNAHD HGFLRTDHTI  60
   61 PCSLYPEEPC SLNIVGPLWI DVSSIVFAAS AISTFLQMAM MVSLGVICDY GNNRRYILFS 120
  121 CVIIGSISGI ILSWSPSSFL LGKIVFLILV DLNFIISQSC YDSFLPIFLR FYPITRGPIT 180
  181 LESALQDETD DLDSYITNTT IDSSEEEPYL LEHSLILNES APPADVEDEH KAKIAARLSS 240
  241 VGFGSFFGAA ILFQIIFTPI LYKTNNNPII LPITVTVCSC WWLILSTPLC TIVTLPVENH 300
  301 SSDAILTLLY NSVKESYHSF KHAMSISSIR LFLFSRLFIN CGIQTSLSSA VIFGKARLNL 360
  361 SNFQLTLLGM GISSFALLGT VIIPYLTEYF QLNSLQVVMI ISILLPMAPL YGLLGYIPGF 420
  421 ENAGIRTSAD VFRATLFFGF FLGGAHSYCR SVYAQLVPSG KETRFFALYA LISQTGVLFS 480
  481 HISLTLISNY TSDLRAVYIF VIVVMTLPLS SLWIMYQHSK TPNLHRSSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..106] deduced N/A No confident structure predictions are available.
    2 View Details [107..529] PSI-BLAST 24.522879 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.01584233411372 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle