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Protein Overview: SPAC2F7.16c

General Information:
Name(s) found: SPAC2F7.16c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • phospholipase D [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1369 amino acids

    Gene Ontology:
    Cellular Component: prospore membrane [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: lipid catabolic process [IEA]
    ascospore-type prospore formation [ISSLink to PubMed article]
    phosphatidylinositol metabolic process [IC]
    exocytosis [ISSLink to PubMed article]
    Molecular Function: phosphatidylinositol-3-phosphate binding [ISS]
    phospholipase D activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIHQGGNSV IDNVPYSLNT NVNDSIYSEK GTGRKDAEDH TPSKITDLEK NVDHSIPSFP  60
   61 ENDPKNYSEF VNLNPPKRPD LEHTRGSSWH TASENVNDLA ANDSTRVQTP EFITQTMEDE 120
  121 NVEVPPLERD ERDAAAAHTS KANRNSARQM WAQLMASVRK FKREDEKPIL KENLPAINLF 180
  181 EAGIPASLPI AKHFIRDKSG QPVLPIITDL IKVSVLDVEP KHNRIHSTFT IQVEYGTGPH 240
  241 AIRWLIYRQL RDFINLHSHF LFFEFQHRFS GRRMKLPKFP KEVLPYLVKL RGYQKILYSN 300
  301 PSDQLIDETH SISDISWESH SQDGDRTTGQ PRHANNGRKK HGNFWTIQGN TLGVYLQEMI 360
  361 HNLQFFPEVN VLYSFLEFSS LGLYLAGAGT FHGKEGFATL KRNYSPTQYM LCCNTTMMKT 420
  421 RSQPFWIIVS ESCIILCDNM LSMQPADVFI WDVDFEITRK NFRKAHSKDT NEKIRLSHHS 480
  481 FKIKNRQKVM KLSVRSGRWL QQFINSVQVA QGLTAWCEIH RFDSFAPVRT NVAVQWMVDA 540
  541 RDHMWNVSRA IKNAKRCIMI HGWWLSPELQ MRRPYSMAHK WRIDRILNEK AHEGVMVYIM 600
  601 IYRNIDATIP IDSFHTKEHL QSLHPNIYVI RSPSHFRQNA LFWAHHEKLV VVDDAITFIG 660
  661 GIDLCFGRYD TPQHILYDDK PVADKTGLCE QTWRGKDYSN ARVHDFFDLT EPYKDMYDRL 720
  721 AVPRMGWHDV SMCIIGQPAR DAARHFVQRW NYLIQCKKPA RKTPLLIPPP DFTTDQLTDS 780
  781 QLTGTCEVQV LRSAGLWSLG LVDTVEQSIQ NAYVTCIEKS EHFIYIENQF FVTSTTCEGT 840
  841 TIENRVGDAL VERIIRAHKN NEKWRGVIMI PLLPGFEGQI DLQEGGSLRL IVECQYRSIC 900
  901 HGEHSIFGRL NAKGIDGSKY LRFYGLRGWA HLGENHELVT EMIYVHAKIL IADDRVAVIG 960
  961 SANINERSLL GNRDSEIAAV IRDTLTIDSK MDGKPYKVGK FAHTLRKRLM REHLGLETDV1020
 1021 LEQREYNMDG LDRDTEWKRV EVWTPDEGNA INGSAYTAEE LKMKYRSQSQ FTTTPDILRK1080
 1081 AEKSMKKLDQ RVSLIPSSIE FNIKTQKDKV EFEKNYEKSK KGPDVIANAL VGGIPLSLKT1140
 1141 KEDSLYELSK FSQCGEDQRP MVLKDPDHLV PEPSRPHCGN GLVFYDDIPL LEVNPISGET1200
 1201 IPKFDASSFE DPVCDEFFED IWSKVASNNT TIYRHIFRCV PDDEMLTWES YNEWKKYGKR1260
 1261 FKEEQARWRQ EELSNLHETH EKSENDPKNP KAGSQGSGNT SASEDSKTEK PKTRTNNGLQ1320
 1321 VPDKRVVYDL LRGIRGQLVE LPLKWMSTES NARNWLSSID KIPPLEIYD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run spc19 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..175] MSA 4.037995 View MSA. No confident structure predictions are available.
    2 View Details [176..525] FFAS03 3.44 Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
    3 View Details [526..1023] PSI-BLAST 36.154902 Phospholipase D
    4 View Details [1024..1073] deduced N/A No confident structure predictions are available.
    5 View Details [1074..1284] deduced N/A No confident structure predictions are available.
    6 View Details [1285..1369] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.0857989342765 bayes_pls_golite062009
  • protein binding
    		•  1.98056222560389 bayes_pls_golite062009
  • transporter activity
    		•  1.29925758003665 bayes_pls_golite062009
  • phospholipid binding
    		•  0.864843473490307 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.552872712432362 bayes_pls_golite062009
  • phosphoinositide binding
    		•  0.45899353522401 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.432003190263252 bayes_pls_golite062009
    3
    Term Confidence Notes
  • phosphoric diester hydrolase activity
    		•  1.55477881010087 bayes_pls_golite062009
  • catalytic activity
    		•  1.29236214516383 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.97354820978871 bayes_pls_golite062009
  • binding
    		•  0.782852985815333 bayes_pls_golite062009
  • protein binding
    		•  0.438178121330569 bayes_pls_golite062009
  • transferase activity
    		•  0.417847571627092 bayes_pls_golite062009
  • kinase activity
    		•  0.41582825017763 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.398900256450913 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle