Protein Overview: trm1

General Information:
Name(s) found:	trm1 / SPBC25D12.05 [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	gi\|6901242\|emb\|CAA20101.2\| N2,N2-dimethylguanosine tRNA methyltransferase [Schizosaccharomyces pombe] [NCBI NR] gi\|19113339\|ref\|NP_596547.1\| N2,N2-dimethylguanosine tRNA methyltransferase [Schizosaccharomyces pombe] [NCBI NR] gi\|12643830\|sp\|Q9P804.1\|TRM1_SCHPO RecName: Full=N(2),N(2)-dimethylguanosine tRNA methyltransferase; AltName: Full=tRNA(guanine-26,N(2)-N(2)) methyltransferase; AltName: Full=tRNA 2,2-dimethylguanosine-26 methyltransferase; AltName: Full=tRNA(m(2,2)G26)di [NCBI NR] N2,N2-dimethylguanosine tRNA methyltransferase [Sanger Pombe] N(2),N(2)-dimethylguanosine tRNA methyltransferase OS=Schizosaccharomyces pombe GN=trm1 PE=1 SV=1 [Swiss-Prot] N2,N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE: O74566;Q9P804; [pompepVF.fasta] N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) [pompep4896] \|trm1\|\|N2,N2-dimethylguanosine tRNA methyltransferase [pompepnew.fasta] \|trm1\|\|N2,N2-dimethylguanosine tRNA methyltransferase\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] N2,N2-dimethylguanosine tRNA methyltransferase [Schizosaccharomyces pombe]gi\|6901242\|emb\|CAA20101.2\| SPBC25D12.05 [Schizosaccharomyces pombe]gi\|12643830\|sp\|Q9P804\|TRM1_SCHPO N(2),N(2)-dimethylguanosine tRNA methyltransferase (tRNA(guanine-26,N(2)-N(2)) [nrdb_11152004_Chlamydomonas] (Q9P804) N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) [pompep4896_normal_reversed] SPBC25D12.05 [Schizosaccharomyces pombe] [nr-271106-contam.fasta] hypothetical protein SPBC25D12.05 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] N(2),N(2)-dimethylguanosine tRNA methyltransferase (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) [nr-271106-contam.fasta] tRNA (guanine(26)-N(2))-dimethyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=trm1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	548 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] nuclear membrane [ISS] mitochondrion [IDA][ISS]
Biological Process:	tRNA processing [ISS] tRNA methylation [ISS]
Molecular Function:	RNA binding [IEA] tRNA (guanine-N2-)-methyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYEANMLRLS QRISNAVNHF STAMMSGASA SLTEGSAIIP FSNPNEVFYN PVQQFNRDLS  60
   61 VTAIRAWSET RSKKIVAKSH HRHQLLDQNS ELSQENLTKC DTTHDFEKNC SEKTDSTSAD 120
  121 NIAGFTILEA LSATGLRSIR YAKELPNVKR ILANDLLENA VKTIEKNVNY NNVSDIVIPN 180
  181 KGDANAVMHM NKFHYDVIDL DPYGSAAPFL DAAVQSVSKD GLLCITCTDS AVLAGNAYPE 240
  241 KCFSNYGGSS LRSNFCHEQA VRHLLYAIAA SAAKYGRAIK PLLSLSIDFY FRVFVQIKAK 300
  301 PVLVKNLQSQ SLLIYHCSGC GSFAEQPLGK TSPGRLPGTT KFSNASGPPV SANCEHCGYV 360
  361 HHVGGPLWGG PLHDAEFLKK MRAIAEDLDP EVYGTKRRIL GMLALADEEL PDVPFYFVLS 420
  421 QICSVLRSQS PPQNIFVSAL LNAGYRVSGS HAKSNAIKTN APWSFVWDVL RSWIKDHPVK 480
  481 LENISKTSAG AAILEKTPTA EVDFTFRPDS EFASKKEGYT RYQMNPTENW GPKSKPGKRT 540
  541 IAEVDSKS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
N-methyltransferase activity	4.07806017452628	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
protein methyltransferase activity	3.92746815303714	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
histone methyltransferase activity	2.99461585647365	bayes_pls_golite062009
tRNA methyltransferase activity	2.5931020126592	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.44201549586712	bayes_pls_golite062009
arginine N-methyltransferase activity	2.41876112831625	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	2.41876112831625	bayes_pls_golite062009
DNA-methyltransferase activity	2.39581687084457	bayes_pls_golite062009
rRNA methyltransferase activity	2.29640050660273	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	2.04296107639729	bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity	1.88889414729709	bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity	1.88889414729709	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.66871163498737	bayes_pls_golite062009
tRNA (guanine-N2-)-methyltransferase activity	1.5444293148467	bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity	1.29759910099835	bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity	1.29759910099835	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	1.1103522853299	bayes_pls_golite062009
transcription regulator activity	0.914549843668268	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.89325812193225	bayes_pls_golite062009
DNA binding	0.86027591375666	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
nucleic acid binding	0.616949327277483	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.533090627724779	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.455449410561251	bayes_pls_golite062009
RNA binding	0.417524996559564	bayes_pls_golite062009
binding	0.383237930789959	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..548]	PSI-BLAST	70.522879	No description for 2dulA was found.

Protein Overview: trm1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: