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Protein Overview: tnr3

General Information:
Name(s) found: tnr3 / SPAC6F12.05c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • thiamine diphosphokinase Tnr3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 569 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article][ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: thiamin diphosphate biosynthetic process [IC]
    negative regulation of thiamin biosynthetic process [IMPLink to PubMed article]
    Molecular Function: thiamin diphosphokinase activity [IGILink to PubMed article][ISS]
    ATP binding [IEA]
    hydrolase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMSSITSAK QLNAEELLDE CDSFNGEFVP GTIPFRANGA AIGYVTPLVL EILIKADNFK  60
   61 FNWVYVPGEY IEINASTFEK RTDILAKVLE HWRHNNTFGI ADQWRNELYT VYGKSKKPVL 120
  121 AVERGGFWLF GFLSTGVHCT MYIPATKEHP LRIWVPRRSP TKQTWPNYLD NSVAGGIAHG 180
  181 DSVIGTMIKE FSEEANLDVS SMNLIPCGTV SYIKMEKRHW IQPELQYVFD LPVDDLVIPR 240
  241 INDGEVAGFS LLPLNQVLHE LELKSFKPNC ALVLLDFLIR HGIITPQHPQ YLQTLERIHR 300
  301 PLPVPVGKYE RGDSFEDTSK KAETCVPAKP QKATHQLAPC KAWLRDYDTD QKFAVLLLNQ 360
  361 PIDIPDDRFR TLWKRASIRV CADGGANQLR NYDSSLKPDY VVGDFDSLTD ETKAYYKEMG 420
  421 VNIVFDPCQN TTDFMKCHKI IKEHGIDTIF VLCGMGGRVD HAIGNLNHLF WAASISEKNE 480
  481 VFLLTELNVS TLLQPGINHV DCHDNIGLHC GLLPVGQSVY VKKTSGLEWN IEDRICQFGG 540
  541 LVSSCNVVTK ATVTIEVNNF IVWTMETRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..284] PSI-BLAST 18.30103 Crystal structure of NADH pyrophosphatase (1790429) from Escherichia coli k12 at 2.20 A resolution
    2 View Details [285..569] PSI-BLAST 70.522879 Thiamin pyrophosphokinase, substrate-binding domain; Thiamin pyrophosphokinase, catalytic domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.57

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle