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Protein Overview: end4

General Information:
Name(s) found: end4 / SPAC688.11 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • Huntingtin-interacting protein homolog [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1092 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cell cortex of cell tip [IDALink to PubMed article]
    actin cortical patch [IDALink to PubMed article]
    Biological Process: fungal-type cell wall organization [IMPLink to PubMed article]
    cortical actin cytoskeleton organization [IMPLink to PubMed article]
    bipolar cell growth [IMPLink to PubMed article]
    membrane raft distribution [IMPLink to PubMed article]
    endocytosis [IMPLink to PubMed article]
    establishment or maintenance of actin cytoskeleton polarity [IMPLink to PubMed article]
    actin cytoskeleton organization [IMPLink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    Molecular Function: phosphatidylinositol-4,5-bisphosphate binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]
    actin binding [ISSLink to PubMed article]
    protein binding, bridging [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSDASLMTS VRKATSIDET APKRKHVRSC IIFTWDHHTA RPFWTAIKVQ PLLANEVQTF  60
   61 KALITIHRVL QEGHKSALVD SQSEKGWLKT CERQYDGESS PKGYSDLIRD YVDYLLDKLS 120
  121 FHAQHPEFNG TFEYKEYISL RQVDDPNEGY ETVYDMMNLQ DHIDEFQKQL FSNFKRSNKN 180
  181 ECRIAALVPL VQESYGIYRF LTSMLRALYS TVDAPETLEP LKHRYKSQHH RLRQFYADCS 240
  241 NLRYLTSLIS VPRLPHDPPD LEGDDNIPDL PKRPASIAPQ PTGASTIAPQ PTGTSPSPPV 300
  301 EMNFPDTSDI TPAYSEPEPI QDFWSDPTLD QQLAAQQAAQ QAAQQQAELA AQQAAAQQAQ 360
  361 LAAQQAAEME RQRMAAQQHQ QALEAIQMAQ AEQQRIAQEQ LAQQQFQMQT QGQLAELEQQ 420
  421 LLATRGQLEQ SNVLLNQYDA RVRTLENELS QAGVNLQEQI HQNDDLIESL KNQILTWKNK 480
  481 YEALAKLYTQ LRQEHLDLLS KYKQIQLKAS SAQEAIDKKE KMEREMKNKN LELADMILER 540
  541 DRARHELETM HRSQRDKQES TERELRLLQE KAASLERNKS SEVSNLLSRY NTEVAHLEDA 600
  601 LHSKDRELAN LGVELKSTEN RYRQLLQEKE EELEIQKAAV DESLLQLSKL QLDRNDIDQA 660
  661 MDTQIDELLK SQLEKLDDIV DSVLATGIQR LDTSLYELDS PMHAGNQYAT PEFILSTIEN 720
  721 ASNNATDFST AFNNYFADGP NADHSEVING VNLFSTAIYE VANNAKGLSR TTGDDQGSDR 780
  781 FVGLSRDLVN MAKRFLSSLF SVNTRKMDVN VKTDLVIGEN IELQRYLQQL TQYSEKFLNK 840
  841 ESENTVGLLN APGENIEELV DNQLAETAQA IQQAILRLQN IAAKPKDDSL SPSELQVHDS 900
  901 LLSASIAITE AIARLIKAAT ASQAEIVAQG RGSSSRGAFY KKHNRWTEGL ISAAKAVARA 960
  961 TTTLIETADG VVNGTSSFEH LIVACNGVSA ATAQLVAASR VKANFASKVQ DHLEDAAKAV1020
 1021 TEACKALVRQ VESVALKAKE VQHEDFSSLG VHEYRRKEIE QQVQILKLEN DLVAARRRLF1080
 1081 DMRKTSYHVA EE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..408] PSI-BLAST 27.69897 Heavy meromyosin subfragment
    2 View Details [409..709] PSI-BLAST 4.522879 No description for 2i1jA was found.
    3 View Details [710..806] deduced N/A No confident structure predictions are available.
    4 View Details [807..1092] FFAS03 6.01 HIP1R THATCH DOMAIN CORE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • clathrin binding
    		•  6.05193509168143 bayes_pls_golite062009
  • protein binding
    		•  2.56515310489265 bayes_pls_golite062009
  • binding
    		•  2.30534322403186 bayes_pls_golite062009
  • phospholipid binding
    		•  2.25660174911946 bayes_pls_golite062009
  • phosphoinositide binding
    		•  1.85796661308258 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.61496023837625 bayes_pls_golite062009
  • actin binding
    		•  1.54582237488591 bayes_pls_golite062009
  • lipid binding
    		•  1.08971787423534 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle