Protein Overview: sen1

General Information:
Name(s) found:	sen1 / SPAC6G9.10c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T39072 DNA2-NAM7 helicase family protein - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|2842700\|sp\|Q92355.1\|SEN1_SCHPO RecName: Full=Helicase sen1 [NCBI NR] gi\|19115031\|ref\|NP_594119.1\| splicing endonuclease Sen1 [Schizosaccharomyces pombe] [NCBI NR] gi\|1644322\|emb\|CAB03612.1\| ATP-dependent 5' to 3' DNA/RNA helicase Sen1 [Schizosaccharomyces pombe] [NCBI NR] ATP-dependent 5' to 3' DNA/RNA helicase Sen1 [Sanger Pombe] Helicase sen1 OS=Schizosaccharomyces pombe GN=sen1 PE=1 SV=1 [Swiss-Prot] DNA2/NAM FAMILY DEAD-BOX TYPE RNA HELICASE; PUTATIVE POSITIVE EFFECTOR OF TRNA-SPLICING ENDONUCLEASE; REQUIRED FOR INTRON CLEAVAGE OF TRNAS; POSSIBLY INVOLVED IN SNRNA AND SNORNA MATURATION; SIMILAR TO S. CEREVISIAE SEN1: Q92355; [pompepVF.fasta] DNA2/NAM FAMILY DEAD-BOX TYPE RNA HELICASE; PUTATIVE POSITIVE EFFECTOR OF TRNA-SPLICING ENDONUCLEASE; REQUIRED FOR INTRON CLEAVAGE OF TRNAS; INVOLVED IN SNRNA AND SNORNA MATURATION; BY SIMILARITY TO S. CEREVISIAE SEN1: Q92355; [pompepV13] Endonuclease sen1 [pompep4896] \|sen1\|\|DNA2/NAM family DEAD-box type RNA helicase [pompepnew.fasta] Helicase sen1 (EC 3.6.1.-) (Endonuclease sen1) [4896.FASTAC] \|sen1\|\|DNA2/NAM7 family\|Schizosaccharomyces pombe\|chr 1\|\|\|Manual [pombe041504.fasta] DNA2-NAM7 helicase family protein [Schizosaccharomyces pombe]gi\|1644322\|emb\|CAB03612.1\| SPAC6G9.10c [Schizosaccharomyces pombe]gi\|2842700\|sp\|Q92355\|SEN1_SCHPO Helicase sen1 (Endonuclease sen1)gi\|7490496\|pir\|\|T39072 DNA2-NAM7 helicase family protein - f [nrdb_11152004_Chlamydomonas] (Q92355) Endonuclease sen1 [pompep4896_normal_reversed] \|sen1\|\|ATP-dependent 5' to 3' DNA/RNA helicase Sen1\|Schizosaccharomyces pombe\|chr 1\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] Helicase sen1 (Endonuclease sen1) [nr-271106-contam.fasta] SPAC6G9.10c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] hypothetical protein SPAC6G9.10c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] Helicase sen1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sen1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	1687 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS]
Biological Process:	snRNA processing [ISS] tRNA processing [ISS] snoRNA processing [ISS] rRNA processing [ISS] termination of RNA polymerase II transcription [ISS] regulation of transcription termination [IC]
Molecular Function:	ATP binding [IC] DNA-dependent ATPase activity [IDA] ATP-dependent 5'-3' DNA helicase activity [IDA] RNA-dependent ATPase activity [IDA] ATP-dependent 5'-3' RNA helicase activity [IDA] RNA polymerase II transcription termination factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAENLSDQDC FEKLSSSKEG QHWFCSGLLT QYIQPTFFWF AHDETPSFKW VLNAYHERLR  60
   61 SCTSCIQAYY ELRNESLAKG SYSFTGFSIT DLQEKWNKWD IIRVLEDFKA LEDETIDFTS 120
  121 LPCLIFETLL NPKLFTCKNI YKNAIDAFNG LLSDWCSNIF LPGYLLFFYE ASHPDVLEWV 180
  181 HSFFKENTEI RISSATVDAV FNTVVFESQN SSDSDCNFVS ISSPEFWERT YMFLELLPLQ 240
  241 SITAACESIL KDYLLNLVKT SESLSSQQMS CLRICCNSSS FWSAADSFKE VSSFLKNLLK 300
  301 NVTATPFEVS DMNWAYIIAS FFRTCLNDFV SVFPEWLKGF VEEKRTIGFI IYSVLDALFD 360
  361 LLSLDYSSPS FLNNTLSLMN ANSITILQDY PEYMLKLRLH SLLYDIAFIS WSHKAITKNP 420
  421 SFVFDPSYEL SPFWKLDNLQ EEKISDVLFS KISSCCFAHD IEISENSTPS GTMVQFAELW 480
  481 QVMSEYISGF LKGFSEKSST EISNMLGDSS KFDTVVSFLL SPTQPLYVSA FHIVQIITNC 540
  541 TKNRNEALKK LVAMDFRGIV HGLADAVLNW QSILSFFPAL RIMRFLSITN KSLSSDNSAF 600
  601 TENDIPTLGA YWQCIWNILD LVFSNVARWS LNNPADTVKA LMKLTLKFVD DLFQNDGIFI 660
  661 KLLAKFDSLI LLGETSESLF SFIMWLKIND LELRGIVINS LCKLFTKFSN FDYLFEDRTV 720
  721 TFLTDFIIRK QKAHLSADQC KQLANVLTQA SPEAKTVLEQ HRLSEMRKTK KQTELTNSAH 780
  781 VIKPSPTPQI TVKQNTTKSS SAPRMGMLEQ LKQEYLTKRN FESKLKSSAV SSRKPTFNEV 840
  841 KPANLLAEDL SDNEDDIDRK QGLFSLAKAN KIPEIRQQER RQVQLLSNST IKMHPSQIRM 900
  901 MTNRNVANVK ARLFPSMTDF YKEILSWEPA NQSPNPVLKF HKLDGKIIDS FKTVEHYMEV 960
  961 LQPMIFMECW SQIQSTKLDL KFSPVEGIMV ERTAVNNFVD IGVSVAPKDL YGYPLYDTEV1020
 1021 VSLAFNKEDA SSMKGLCCFA KVERIVRQTN GVLVVLRTLP SMEILNKLQG NCALWFLKLT1080
 1081 NLATFTRQYA GIRGLPYFHL ADDIIRARPC SQPVKHSSSE IKAAMKRYQV NEPQAKAIMC1140
 1141 ALDNNGFTLI QGPPGTGKTK TIIGIISALL VDLSRYHITR PNQQSKSTES KQQILLCAPS1200
 1201 NAAVDEVLLR LKRGFLLENG EKYIPRVVRI GNPETINVSV RDLSLEYQTE KQLLEVNQGA1260
 1261 IDLGSLQELT RWRDTFYDCI QKIEELEKQI DVARDVAEDT KSLGKELQNK INEKNLAEQK1320
 1321 VEELQSQSFT KNKEVDLLRK KAQKAILKQA DVVCATLSGS GHDLVAHSSL NFSTVIIDEA1380
 1381 AQAVELDTII PLRYGAKKCI LVGDPNQLPP TVLSKKAASL NYSQSLFVRI QKNFSNQMCL1440
 1441 LSIQYRMHPD ISHFPSKKFY DSRLEDGDNM AEKTQQVWHV NPKFTQYRLF DVRGKERTSN1500
 1501 TMSTYNLEEV EYLVNMVDEL LNKFPDVNFT GRIGVITPYR SQLHELRRAF KVKYGKSFMS1560
 1561 TIDIQTVDGF QGQEKDIIFF SCVKSYSKHG IGFLRDFRRL NVALTRARSS LLIIGNMETL1620
 1621 KTDDLWGSLV DDALSRKLVE SPHIDSEGRL ITISRTSEKR MKNEEFVEPP SKKLANSEPS1680
 1681 KEIRQRS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.88

Protein Overview: sen1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: