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Protein Overview: SPBC409.13

General Information:
Name(s) found: SPBC409.13 [Sanger Pombe]
Description(s) found:
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  • pir||T40440 6,7-dimethyl-8-ribityllumazine synthase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|5731920|emb|CAB52615.1| 6,7-dimethyl-8-ribityllumazine synthase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|30913303|sp|Q9UUB1.1|RIB4_SCHPO RecName: Full=6,7-dimethyl-8-ribityllumazine synthase; Short=DMRL synthase; Short=Lumazine synthase; AltName: Full=Riboflavin synthase beta chain [NCBI NR]
  • gi|22219146|pdb|1KYY|E Chain E, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [NCBI NR]
  • gi|22219145|pdb|1KYY|D Chain D, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [NCBI NR]
  • gi|22219144|pdb|1KYY|C Chain C, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [NCBI NR]
  • gi|22219143|pdb|1KYY|B Chain B, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [NCBI NR]
  • gi|22219142|pdb|1KYY|A Chain A, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [NCBI NR]
  • gi|22219141|pdb|1KYX|E Chain E, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [NCBI NR]
  • gi|22219140|pdb|1KYX|D Chain D, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [NCBI NR]
  • gi|22219139|pdb|1KYX|C Chain C, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [NCBI NR]
  • gi|22219138|pdb|1KYX|B Chain B, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [NCBI NR]
  • gi|22219137|pdb|1KYX|A Chain A, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [NCBI NR]
  • gi|22219136|pdb|1KYV|E Chain E, Lumazine Synthase From S.Pombe Bound To Riboflavin [NCBI NR]
  • gi|22219135|pdb|1KYV|D Chain D, Lumazine Synthase From S.Pombe Bound To Riboflavin [NCBI NR]
  • gi|22219134|pdb|1KYV|C Chain C, Lumazine Synthase From S.Pombe Bound To Riboflavin [NCBI NR]
  • gi|22219133|pdb|1KYV|B Chain B, Lumazine Synthase From S.Pombe Bound To Riboflavin [NCBI NR]
  • gi|22219132|pdb|1KYV|A Chain A, Lumazine Synthase From S.Pombe Bound To Riboflavin [NCBI NR]
  • gi|19112255|ref|NP_595463.1| 6,7-dimethyl-8-ribityllumazine synthase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • 6,7-dimethyl-8-ribityllumazine synthase [Sanger Pombe]
  • 6,7-dimethyl-8-ribityllumazine synthase OS=Schizosaccharomyces pombe GN=rib4 PE=1 SV=1 [Swiss-Prot]
  • 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE; DMRL SYNTHASE FAMILY; SIMILAR TO S. CEREVISIAE RIB4: Q9UUB1; [pompepVF.fasta]
  • 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE; DMRL SYNTHASE FAMILY: Q9UUB1; [pompepV13]
  • 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9) (DMRL synthase) (Lumazine synthase) (Riboflavin synthase beta chain) [pompep4896]
  • |||putative 6,7-dimethyl-8-ribityllumazine synthase [pompepnew.fasta]
  • |||6,7-dimethyl-8-ribityllumazine synthase (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • 6,7-dimethyl-8-ribityllumazine synthase; DMRL synthase family [Schizosaccharomyces pombe]gi|5731920|emb|CAB52615.1| SPBC409.13 [Schizosaccharomyces pombe]gi|22219146|pdb|1KYY|E Chain E, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedionegi|222 [nrdb_11152004_Chlamydomonas]
  • |||6,7-dimethyl-8-ribityllumazine synthase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (Q9UUB1) 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9) (DMRL synthase) (Lumazine synthase) (Riboflavin synthase beta chain) [pompep4896_normal_reversed]
  • 6,7-dimethyl-8-ribityllumazine synthase (DMRL synthase) (Lumazine synthase) (Riboflavin synthase beta chain) [nr-271106-contam.fasta]
  • Chain E, Lumazine Synthase From S.Pombe Bound To Riboflavin [nr-271106-contam.fasta]
  • Chain E, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [nr-271106-contam.fasta]
  • 6,7-dimethyl-8-ribityllumazine synthase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Chain A, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [nr-271106-contam.fasta]
  • Chain B, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [nr-271106-contam.fasta]
  • Chain C, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [nr-271106-contam.fasta]
  • Chain D, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [nr-271106-contam.fasta]
  • Chain D, Lumazine Synthase From S.Pombe Bound To Riboflavin [nr-271106-contam.fasta]
  • Chain B, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [nr-271106-contam.fasta]
  • Chain D, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [nr-271106-contam.fasta]
  • Chain A, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [nr-271106-contam.fasta]
  • 6,7-dimethyl-8-ribityllumazine synthase (predicted); DMRL synthase family; similar to S. cerevisiae YOL143C [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Chain A, Lumazine Synthase From S.Pombe Bound To Riboflavin [nr-271106-contam.fasta]
  • Chain E, Lumazine Synthase From S.Pombe Bound To Nitropyrimidinedione [nr-271106-contam.fasta]
  • Chain C, Lumazine Synthase From S.Pombe Bound To Riboflavin [nr-271106-contam.fasta]
  • Chain B, Lumazine Synthase From S.Pombe Bound To Riboflavin [nr-271106-contam.fasta]
  • Chain C, Lumazine Synthase From S.Pombe Bound To Carboxyethyllumazine [nr-271106-contam.fasta]
  • 6,7-dimethyl-8-ribityllumazine synthase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rib4 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 159 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [IDALink to PubMed article][ISSLink to PubMed article]
    riboflavin synthase complex [IEA]
    Biological Process: riboflavin biosynthetic process [ISSLink to PubMed article]
    Molecular Function: 6,7-dimethyl-8-ribityllumazine synthase activity [ISSLink to PubMed article]
    riboflavin synthase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSGIKGPNP SDLKGPELRI LIVHARWNLQ AIEPLVKGAV ETMIEKHDVK LENIDIESVP  60
   61 GSWELPQGIR ASIARNTYDA VIGIGVLIKG STMHFEYISE AVVHGLMRVG LDSGVPVILG 120
  121 LLTVLNEEQA LYRAGLNGGH NHGNDWGSAA VEMGLKALY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] PSI-BLAST 49.69897 Lumazine synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 6,7-dimethyl-8-ribityllumazine synthase activity
    		•  5.61825642183907 bayes_pls_golite062009
  • intramolecular transferase activity, transferring acyl groups
    		•  4.02275160603209 bayes_pls_golite062009
  • catalytic activity
    		•  1.78070169551865 bayes_pls_golite062009
  • riboflavin synthase activity
    		•  1.72639804812167 bayes_pls_golite062009
  • isomerase activity
    		•  0.268840799327499 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle