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Protein Overview: spb1

General Information:
Name(s) found: spb1 / SPAC1687.11 [Sanger Pombe]
Description(s) found:
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  • gi|9910811|sp|O42832.2|SPB1_SCHPO RecName: Full=AdoMet-dependent rRNA methyltransferase spb1; AltName: Full=2'-O-ribose RNA methyltransferase; AltName: Full=S-adenosyl-L-methionine-dependent methyltransferase [NCBI NR]
  • pir||T37754 pmt2 methyltransferase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|4106665|emb|CAA22605.1| rRNA methyltransferase Spb1 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114041|ref|NP_593129.1| rRNA methyltransferase Spb1 (predicted) [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • rRNA methyltransferase Spb1 [Sanger Pombe]
  • AdoMet-dependent rRNA methyltransferase spb1 OS=Schizosaccharomyces pombe GN=spb1 PE=1 SV=2 [Swiss-Prot]
  • (O42832) AdoMet-dependent rRNA methyltransferase pmt2 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase) (S-adenosyl-L-methionine-dependent methyltransferase) [Swiss-Prot]
  • PMT2 METHYLTRANSFERASE: O42832; [pompepVF.fasta]
  • Probable rRNA methyltransferase pmt2 (EC 2.1.1.-) [pompep4896]
  • |pmt2||putative RNA methyltransferase [pompepnew.fasta]
  • |pmt2||rRNA methyltransferase (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • pmt2 methyltransferase [Schizosaccharomyces pombe]gi|4106665|emb|CAA22605.1| pmt2 [Schizosaccharomyces pombe]gi|9910811|sp|O42832|PMT2_SCHPO Probable rRNA methyltransferase pmt2gi|7492308|pir||T37754 pmt2 methyltransferase - fission yeast (Schizosaccha [nrdb_11152004_Chlamydomonas]
  • |pmt2||rRNA methyltransferase |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O42832) Probable rRNA methyltransferase pmt2 (EC 2.1.1.-) [pompep4896_normal_reversed]
  • |spb1||rRNA methyltransferase Spb1 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC1687.11 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • AdoMet-dependent rRNA methyltransferase spb1 (2'-O-ribose RNA methyltransferase) (S-adenosyl-L-methionine-dependent methyltransferase) [nr-271106-contam.fasta]
  • hypothetical protein SPAC1687.11 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • AdoMet-dependent rRNA methyltransferase spb1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=spb1 PE=1 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 802 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    nucleolus [ISSLink to PubMed article]
    Biological Process: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [ISSLink to PubMed article]
    rRNA methylation [ISSLink to PubMed article]
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [ISSLink to PubMed article]
    Molecular Function: rRNA methyltransferase activity [ISSLink to PubMed article]
    rRNA (uridine-2'-O-)-methyltransferase activity [ISSLink to PubMed article]
    rRNA (guanine) methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKSQKKTAK GRLDKWYKLA KEQGYRSRAA FKLVQLNQKY SFLEKAKVII DLCAAPGGWL  60
   61 QVASKTCKPG SLIVGVDLAP IKPIPNCHTF VEDITSDKCR SQLRGYLKTW KADVVLHDGA 120
  121 PNVGSAWLQD AYGQAQLVLM SMKLACEFLV AGGTFVTKVF RSRDYNNLLW VFKQLFNKVE 180
  181 ATKPPSSRNV SAEIFVVCRG YKAPKKLDPR FTDPRTVFEE VQEPVTNVDA KVFHPEKRKR 240
  241 SREGYADDDY TLHKTVLASE FVTANDPIQI LGTSAEIVFP KDDEECQRLY NLDVTTEEIL 300
  301 LCCSDLQVLG KKEFRDILRW RLKIRDEMGI GKKVEDEQKT VVEEIPEMDE EERLDQELQD 360
  361 LSEAERVKLK RERRKANQRK QREIVRMQMG MLAPMDIGLE HEAMGEDSLF GLATAEKHGL 420
  421 KELENGTLPV TESVDEEVST DNEVEYDSDD ERDRLEADLD SMYSDYTKRK AESDVKYRVK 480
  481 KARGDLDDEE WNGIDNGTES DDSQIAETNF ATPDKDRLTT SLLDKGSTKD GLSRKARMFF 540
  541 DQDIFDGIED ADADVEIMSM NRAAIKKREA ELASQNNDDG SKGDQSEDSN DHIEVVPVAS 600
  601 AHDEDDDWNS DSDNDENNVE IVTAEAMTLA QDIASRRKSK ADLIDEGYNR WSFQSKEGLP 660
  661 DWFLDEETTV NKPNKPITKE AVLALREKMK ALNARPIKKV LEAQGRKKMR TIKRLQRVAK 720
  721 KAEGISESGD MTESEKAKEI SRLVSRATKS KPKAKPTLVV AKGPNKGLKS RPKGVKGKYK 780
  781 MVDSRMKKDL RAQKRLAKKG RR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] PSI-BLAST 67.09691 RNA methyltransferase FtsJ
    2 View Details [207..340] deduced N/A No confident structure predictions are available.
    3 View Details [341..695] PSI-BLAST 16.30103 Heavy meromyosin subfragment
    4 View Details [696..802] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle