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Protein Overview: plc1

General Information:
Name(s) found: plc1 / SPAC22F8.11 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • phosphoinositide phospholipase C Plc1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 899 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: signal transduction [ISSLink to PubMed article]
    regulation of phosphate metabolic process [ISSLink to PubMed article]
    cellular lipid catabolic process [IC]
    cellular response to UV [IMPLink to PubMed article]
    inositol lipid-mediated signaling [ICLink to PubMed article]
    Molecular Function: phosphoinositide phospholipase C activity [TASLink to PubMed article]
    protein binding [IPILink to PubMed article]
    calcium ion binding [ISSLink to PubMed article]
    signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNCEMVTSPE SVNLGDSNRA VSPFCLPDCS ENAVAQTRSK TLDNAALDLP YVGNRKKSEQ  60
   61 DFFKMLSSRD RDAHSTLRKR SNSLSSFLST KSTSASENKF HGGLNWLSLK LNLLLRLQGR 120
  121 MNSARTNTSM NPYSCDSNEN LSTLSSVNQN FNSRQLLATI VPESIQNGCS LLRITKKKVR 180
  181 QRKVSLDPIS GYLMLDKNTG KAYKKLCVDD IKEIRQGRDA RNYREQYKIS SENEKRWFTI 240
  241 IYCADNKLKA MHMISPTLDA HNQWIMALEG LKTYRLNEFI IGLNLVCHQG EKMIDYSENL 300
  301 NPWEKLEKEQ SAQLDLGDVH RMCQMLHLNA SMEFLEETFQ KADADHSGKL SFEEFQHFVS 360
  361 LLKTRSEIVD IFKEYTSGSD KMSLEQFRHF LSTSQKARLD SDSIRTLYVS FCSNDDSKMG 420
  421 LIEFTSFLLS PHNSPVVPVI QDMSRPLNEY LISSSHNTYL LGKQFGGESS IEGYIRSLQR 480
  481 GCKCIEIDCW DGPNGPVVCH GHTFTSMIKF NDVIDAIRKY AFVVSPYPLF ISLEIHCCPD 540
  541 QQRQMVSYMK QAFGDTLVMK PVTANESVLP SPEDLLNKIL LKVKCSATPL HQFSTDILKV 600
  601 GITDSSTDTT ESSELENSEL TGLRKGKRRM KNIIVQELQQ LAPYARSLKF RNFSLPESKT 660
  661 YSHIFSFSER TIKKHGKAMV PRLSKHNLRY LCRVYPGPLR VGSTNFNPQV YWRLGVQMVA 720
  721 LNWQTYDTGL QINDALFIAD PPTGYLLKPP CQRIIGTTVG EEGLPRKIKL TIDVISGQQL 780
  781 RRARELSNSE TLSPYVEIQV HSMEESPFRW CSKVVHENGF RPFWGETMVY ESIISDDFYS 840
  841 MIRFLVHHRG SNGNDSIFAN FTCPIDRLQQ GYRHIRLLDM QGENLLFSSL FLKIKKEDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] deduced N/A No confident structure predictions are available.
    2 View Details [106..287] PSI-BLAST 25.0 Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin
    3 View Details [288..899] PSI-BLAST 167.0 Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle