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Protein Overview: pla1

General Information:
Name(s) found: pla1 / SPBC646.04 [Sanger Pombe]
Description(s) found:
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  • gi|4160340|emb|CAA22808.1| poly(A) polymerase Pla1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|26397523|sp|Q10295.1|PAP_SCHPO RecName: Full=Poly(A) polymerase pla1; Short=PAP; AltName: Full=Polynucleotide adenylyltransferase [NCBI NR]
  • pir||JC6058 poly A polymerase (EC 2.7.7.-) - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19112154|ref|NP_595362.1| poly(A) polymerase Pla1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1419256|emb|CAA56141.1| polymerase [Schizosaccharomyces pombe] [NCBI NR]
  • poly(A) polymerase Pla1 [Sanger Pombe]
  • Poly(A) polymerase pla1 OS=Schizosaccharomyces pombe GN=pla1 PE=2 SV=1 [Swiss-Prot]
  • POLY A POLYMERASE; NUCLEOTIDYLTRANSFERASE; POLYADENYLATION FACTOR; SIMILAR TO S. CEREVISIAE PAP1: Q10295;Q9UU09; [pompepVF.fasta]
  • Poly(A) polymerase pla1 (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase) [pompep4896]
  • |pla1||poly A polymerase [pompepnew.fasta]
  • |pla1||poly(A) polymerase|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • |pla1||poly|Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • poly A polymerase; Nucleotidyltransferase; polyadenylation factor; similar to S. cerevisiae PAP1 [Schizosaccharomyces pombe]gi|4160340|emb|CAA22808.1| poly(A) polymerase; nucleotidyltransferase; involved in polyadenylation (predicted); similar to S. cere [nrdb_11152004_Chlamydomonas]
  • (Q10295) Poly(A) polymerase pla1 (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase) [pompep4896_normal_reversed]
  • SPBC646.04 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • polymerase [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Poly(A) polymerase pla1 (PAP) (Polynucleotide adenylyltransferase) [nr-271106-contam.fasta]
  • poly(A) polymerase [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Poly(A) polymerase pla1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=pla1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 566 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    mRNA cleavage and polyadenylation specificity factor complex [IGILink to PubMed article]
    Biological Process: mRNA export from nucleus [ISSLink to PubMed article]
    mRNA polyadenylation [IGILink to PubMed article]
    Molecular Function: ATP binding [IEA]
    RNA binding [IEA]
    polynucleotide adenylyltransferase activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTKQWGITP PISTAPATEQ ENALNTALIN ELKNQNLFES PAESEKRVKV LDELQQITTE  60
   61 FVKKVSLAKH MNEKMANEAG GKIFTYGSYR LGVYGPGSDI DTLVVVPKHV SRDNFFQDLE 120
  121 PMLREREEVT DLAAVPDAYV PIIKFKFLGI SIDLIFARLS VPRVPRDLEL SDNNLLKGVE 180
  181 ERCVLSLNGT RVTDQILQLV PNRAVFKHAL RAIKFWAQRR AIYANVVGFP GGVAWAMMVA 240
  241 RICQLYPNAV SSVIVAKFFR ILHQWNWPQP ILLKPIEDGP LQVRIWNPKL YPSDKAHRMP 300
  301 IITPAYPSMC ATHNITLSTQ TIILREMVRA GEIADQIMVK ALPWSALFQK HDFFHRYKHY 360
  361 LTITAAAKTA EAQLKWAGLV ESKLRHLVTR LELVDAIALA HPFNKGFDKV YNCSSEEEAQ 420
  421 QVASGVTLEV AYESTDHEKL ANDTVNEEKA DNTESKADGS ENGEKQIFPV YTTTCYIGLE 480
  481 LEKKKGHPIK RLDISWPTQE FYELCKKWDK YDDTLMNVFI KNTKNTALPD EVFEPGEERP 540
  541 KATKKRSTAD TAHSTEQLKR QKVSTA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..566] PSI-BLAST 146.0 No description for 2hhpA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • polynucleotide adenylyltransferase activity
    		•  5.40967709450432 bayes_pls_golite062009
  • RNA binding
    		•  2.46555984694381 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  2.12021443504286 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.43322212500405 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.08480919674453 bayes_pls_golite062009
  • DNA binding
    		•  0.920001549206154 bayes_pls_golite062009
  • binding
    		•  0.888087430062829 bayes_pls_golite062009
  • catalytic activity
    		•  0.75232920999699 bayes_pls_golite062009
  • protein binding
    		•  0.516354942587518 bayes_pls_golite062009
  • transferase activity
    		•  0.432029324907561 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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