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Protein Overview: ptc3

General Information:
Name(s) found: ptc3 / SPAC2G11.07c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • protein phosphatase 2C Ptc3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 414 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    protein serine/threonine phosphatase complex [IEA]
    cytosol [IDALink to PubMed article]
    Biological Process: inactivation of MAPK activity involved in osmosensory signaling pathway [IMPLink to PubMed article]
    protein amino acid dephosphorylation [IDALink to PubMed article]
    Molecular Function: protein serine/threonine phosphatase activity [IDALink to PubMed article]
    magnesium ion binding [IEA]
    manganese ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQTLSEPVT EKHSVNGSNE FVLYGLSSMQ GWRISMEDAH SAILSMECSA VKDPVDFFAV  60
   61 YDGHGGDKVA KWCGSNLPQI LEKNPDFQKG DFVNALKSSF LNADKAILDD DQFHTDPSGC 120
  121 TATVVLRVGN KLYCANAGDS RTVLGSKGIA KPLSADHKPS NEAEKARICA AGGFVDFGRV 180
  181 NGNLALSRAI GDFEFKNSNL EPEKQIVTAL PDVVVHEITD DDEFVVLACD GIWDCKTSQQ 240
  241 VIEFVRRGIV AGTSLEKIAE NLMDNCIASD TETTGLGCDN MTVCIVALLQ ENDKSAWYKK 300
  301 IADRVAANDG PCAPPEYAEN HGPGWRSGDN NKKVIVPPNF HQVKLNGSDG YDKDANENSK 360
  361 EDDSTNGSLA AGFRWKEHFF PHKAEEENSS SETDIVNSNK DVADDHKEAV SAAD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..414] PSI-BLAST 85.30103 CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.29765002420868 bayes_pls_golite062009
  • phosphatase activity
    		•  6.84540130415879 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.63839066304808 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.76293366458633 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  5.66354576593165 bayes_pls_golite062009
  • hydrolase activity
    		•  2.5631136269171 bayes_pls_golite062009
  • binding
    		•  1.74689317666387 bayes_pls_golite062009
  • catalytic activity
    		•  1.53401212718168 bayes_pls_golite062009
  • protein binding
    		•  0.425331902048676 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle