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Protein Overview: nhp2

General Information:
Name(s) found: nhp2 / SPAC1782.10c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • RNA-binding protein Nhp2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 154 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nucleolus [IDALink to PubMed articleLink to PubMed article]
    small nucleolar ribonucleoprotein complex [ISS]
    Biological Process: endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) [IGILink to PubMed article]
    rRNA pseudouridine synthesis [ISS]
    snRNA pseudouridine synthesis [ISS]
    Molecular Function: snoRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKDKKDHKH SGSTEDEYDS YLPALMPIAK PLAPKKLNKK MMKTVKKASK QKHILRGVKE  60
   61 VVKAVRKGEK GLVILAGDIS PMDVISHIPV LCEDNNVPYL YTVSKELLGE ASNTKRPTSC 120
  121 VMIVPGGKKK DMSKVEEYKE SYEEIIKEVP ALEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] PSI-BLAST 28.522879 Crystal Structure of High Mobility Like Protein, NHP2, putative from Cryptosporidium parvum

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • snoRNA binding
    		•  4.95788328272916 bayes_pls_golite062009
  • RNA binding
    		•  4.7078532107994 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  3.68798692352408 bayes_pls_golite062009
  • structural molecule activity
    		•  3.12718364266877 bayes_pls_golite062009
    		• 2.493460131667 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.39301463005357 bayes_pls_golite062009
  • binding
    		•  1.74903521776827 bayes_pls_golite062009
  • mRNA binding
    		•  1.63088955572344 bayes_pls_golite062009
  • catalytic activity
    		•  0.264002643439785 bayes_pls_golite062009
  • protein binding
    		•  0.131685221037103 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle