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Protein Overview: mex67

General Information:
Name(s) found: mex67 / SPBC1921.03c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • mRNA export receptor Mex67 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 596 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nuclear membrane [IDALink to PubMed article]
    nuclear RNA export factor complex [IPILink to PubMed article]
    spindle [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    nuclear pore [ISSLink to PubMed article]
    Biological Process: ribosomal large subunit export from nucleus [ISS]
    poly(A)+ mRNA export from nucleus [IGILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    protein heterodimerization activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRKRERRN AVKENEMVID TPLEKRRTPG KPRATREPPI SVVITGHSKG SEDDLISFVW  60
   61 RKVKVRLMNI SYSPASVTAV VKSQDFSRLN GLNGAAFAGD HLAIRRVDGA SNVTQDYRKA 120
  121 KTKRSFRSVS APSLSALATQ AQRNVSKTLP QSTNETIEKL RQFLQTRYQP ATKFLDLGNL 180
  181 QQDPLLKQMG ILAEASTKSK MFPALMKVAS LNFPDVISVS LSDNNLQSVT AVTTLAQTWP 240
  241 KLLNLSLANN RITSLSDLDP WSPKTKLPEL QELVLVGNPI VTTFANRAMD YQREMVSRFP 300
  301 KLRLLDGNSI NSEIIASQST VPFPVYQSFF DKVETEQIVN SFLAAFFKGW DENRSALVNQ 360
  361 LYSPNATFSI SLNASNVRTN FSQKTDTKKW GAYKMKSRNL LYSQSQKESK SRLFNGHEEI 420
  421 SNAVKSLPAT AHDLSDRSQW VFDGWNLVLP SVGAAIKIVV HGQFEEPQNK RLLRSFDRTL 480
  481 LILPGGSTGI LIINDLLVIR SFAGSLGWLP GQSSVRTSNN AMSASASKPS DIVQPRPEQA 540
  541 MLDTRQQIVL KIKAETGLND YYAHMCCEQN NWDYNSALAS FLELKSRNVI PAEAFS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..303] PSI-BLAST 5.30103 Crystal structure of CD14
    2 View Details [304..486] PSI-BLAST 11.154902 Crystal structure of the C. albicans Mtr2-Mex67 M domain complex
    3 View Details [487..596] PSI-BLAST 46.522879 NTF2-like domain of Tip associating protein, TAP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleocytoplasmic transporter activity
    		•  4.11811310168752 bayes_pls_golite062009
  • protein transporter activity
    		•  3.25560675565407 bayes_pls_golite062009
  • binding
    		•  2.52411158739487 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.19585939185279 bayes_pls_golite062009
  • structural constituent of nuclear pore
    		•  2.18859566641856 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.1539951593359 bayes_pls_golite062009
  • transporter activity
    		•  1.80701285041353 bayes_pls_golite062009
  • structural molecule activity
    		•  1.60851232976006 bayes_pls_golite062009
  • mRNA binding
    		•  1.48678274024408 bayes_pls_golite062009
  • protein binding
    		•  1.34243535208605 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.33804818542017 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.22102896992563 bayes_pls_golite062009
  • Ran GTPase binding
    		•  1.18290069522408 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.890150150408175 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.77053580490303 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.77053580490303 bayes_pls_golite062009
  • RNA binding
    		•  0.47499792472996 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.446562877324676 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.439519001457896 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.430285640125175 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.45

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle