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Protein Overview: mis4

General Information:
Name(s) found: mis4 / SPAC31A2.05c [Sanger Pombe]
Description(s) found:
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  • gi|914883|emb|CAA90463.1| cohesin loading factor Mis4 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|4239919|dbj|BAA74749.1| Mis4 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||S59644 sister chromatid cohesion molecule Mis4p - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19113829|ref|NP_592917.1| cohesin loading factor Mis4 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|1175399|sp|Q09725.1|MIS4_SCHPO RecName: Full=Sister chromatid cohesion protein mis4; AltName: Full=SCC2 homolog [NCBI NR]
  • cohesin loading factor Mis4 [Sanger Pombe]
  • Sister chromatid cohesion protein mis4 OS=Schizosaccharomyces pombe GN=mis4 PE=1 SV=1 [Swiss-Prot]
  • ADHERIN; SISTER CHROMATID COHESION MOLECULE; ASSOCIATES WITH CHROMATIN; SIMILAR TO S. CEREVISIAE SCC2: Q09725; [pompepVF.fasta]
  • SISTER CHROMATID COHESION MOLECULE MIS4P: Q09725; [pompepV13]
  • Sister chromatid cohesion protein mis4 [pompep4896]
  • |mis4||adherin [pompepnew.fasta]
  • Sister chromatid cohesion protein mis4 (SCC2 homolog) [4896.FASTAC]
  • |mis4||adherin|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • sister chromatid cohesion molecule Mis4p [Schizosaccharomyces pombe]gi|914883|emb|CAA90463.1| SPAC31A2.05c [Schizosaccharomyces pombe]gi|4239919|dbj|BAA74749.1| Mis4 [Schizosaccharomyces pombe]gi|2130416|pir||S59644 sister chromatid cohesion molecule M [nrdb_11152004_Chlamydomonas]
  • (Q09725) Sister chromatid cohesion protein mis4 [pompep4896_normal_reversed]
  • |mis4||cohesin loading factor Mis4|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Mis4 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • SPAC31A2.05c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC31A2.05c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
    • Organism: Schizosaccharomyces pombe
    Length: 1583 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article][IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    chromosome [IDALink to PubMed article]
    mitotic cohesin complex [IDALink to PubMed article]
    cohesin loading complex [IMPLink to PubMed article]
    condensed nuclear chromosome [ICLink to PubMed article]
    Biological Process: positive regulation of maintenance of mitotic sister chromatid cohesion [IMPLink to PubMed article]
    sister chromatid cohesion [IGILink to PubMed article]
    S phase of mitotic cell cycle [IMPLink to PubMed article]
    mitotic spindle organization [IMPLink to PubMed article]
    attachment of spindle microtubules to kinetochore [IMPLink to PubMed article]
    mitotic sister chromatid cohesion [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPETFKKVN SSNRIIKGLQ YTPLASSIPL ENGLQNVLYP SSKFQNEPLQ LNSEESSIMQ  60
   61 RYVDMLNPGA TFVNDSETFN FYKNALSAMI TEPAMPAMRV NASPVLDQKV CNSDSLSELN 120
  121 DFTKSLIQPS MLMCEPKEKP DASSINTNRS SSDNGFLTPS SSPRSPSCSR VFNAVQLCSP 180
  181 KKSKDDITTP KKRLMEDTYS PRESPSKIQR LQDVLLKQLQ DTRLLISQVI EAENSEDFSS 240
  241 NSLFIKREDD DGKHISSHAI EKLYMALTKL SRLGACDKLL EEGSIILVKQ ILEKELKELP 300
  301 VACYSIINLH DSLTQFPNLD FILKTTALVL FIIFLVPSFK KLQNEESILH LLNILHSIFE 360
  361 YTVPEAIDNI VQSKTSDART SEIQHLSVLL QKVANVLNIL SKVAHEIPLS EAVVIRIVYL 420
  421 FPKVSTLDNS FKTKLPNCNS SSFDFLKAPL FQTLQYLFRL YPYQRDFIIE ESLTNFSHLP 480
  481 TARSVSRTYR LSNGKSIQYY STLFVRLIQS CSIQNLFDSE IVQSESKSTE ALHSGNLTEH 540
  541 LKTVESILSK SRHEEYRIAN HIVAYLLSRS LKQNKTESDN SFAILTKILL EDLLNMLSLP 600
  601 EWCGTETIIR QFAMNLVMTV TNDKQAVSSK NAALDLISLI VNKVLALFDL SLFEKHNIPA 660
  661 PTNFNDIISF IPSITRLNEL SQVSFNHFYF LCKGDISLEN ILPYNYNKWF SFLLQLRKVC 720
  721 NDSEALKIID NCIDKNMQKS QEGFQGPSPF KADENDEDIF IISLYHSSLF LNLKFFVSLI 780
  781 IGFLDSPQAS LRTKCLRIIN QMKTIPSILR THPEVLAQII SKSNDQSAIV RDTVLDLLGT 840
  841 YIMAYRETIP QIYGCIISGI SDPSTIVRKR AIKQLCEVYE ATEDLNIRVD IASKLLTRSN 900
  901 DEEETISELS LEVLEKLWFS PASNELDCQK GYEQLTFLEK QKLRVQYFPI LKLCAEPSTE 960
  961 RHVLLVTSLK TMLTSKEEIN LSTLHTQIRL LLSCLFNQLI EVVTEDQVDE STKGILYEIM1020
 1021 STLFVFSRAF PFLFDLSYLH LLKPYLRSAS TIEEQRFLYY VVAIFRQVLP FQKEISESFL1080
 1081 RSLESVLLQR LTKAGTATLM EIVPCLCSLF TRLNDYERLK KIVVSCLKSL EEARHSENNF1140
 1141 QKMVRLIDLI GLFSRYGDLN RINDDWKHSL DFISPECDDA YVILLGYFQK LLKDAKGQLR1200
 1201 IHIIDNMSRI CLRETSLFIS PLMLSTLDMI IAENNVNEVS VLFKSFLELL AADEDLIFEA1260
 1261 DQKLSLKGKQ NVQSNKSVDR DMLKGTKDKQ WIEGVSASLM QHFLPCILDS CFSKNLRYSM1320
 1321 LGIEILKCII HQGLVNPRMC FSTIIALESN AIKETREVAI LLHTELHRRH ESLIDGLYAQ1380
 1381 SADLIFSLQK TEEYQTFKLG EFSPFQSAYT IVSADKSSKS RKKLIMQILK PLKLDGIDLP1440
 1441 SFTEEKVSFV SFCCVCLAGI PYVSIEEPLM IISTVDSVLA TIGPTITGWM KKLDHERFKI1500
 1501 LAGINLCNLI YLKRYIKYAF SISDSSRPIR EKKPLTLLNR GYVDLITSDA KPDIVSKLVI1560
 1561 KLFEEENILS GEDQVEGEQL TVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.76

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle