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Protein Overview: mad2

General Information:
Name(s) found: mad2 / SPBC20F10.06 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • spindle checkpoint protein Mad2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 203 amino acids

    Gene Ontology:
    Cellular Component: condensed nuclear chromosome kinetochore [TASLink to PubMed article]
    mitotic checkpoint complex [IDALink to PubMed article]
    nuclear pore [ISSLink to PubMed article]
    Biological Process: mitotic cell cycle spindle assembly checkpoint [IMPLink to PubMed article]
    negative regulation of mitotic metaphase/anaphase transition [IPILink to PubMed article]
    inhibition of mitotic anaphase-promoting complex activity [IPILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    anaphase-promoting complex binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSVPIRTNF SLKGSSKLVS EFFEYAVNSI LFQRGIYPAE DFKVVRKYGL NMLVSVDEEV  60
   61 KTYIRKIVSQ LHKWMFAKKI QKLILVITSK CSGEDLERWQ FNVEMVDTAD QFQNIGNKED 120
  121 ELRVQKEIQA LIRQITATVT FLPQLEEQCT FNVLVYADKD SEVPTDWVDS DPRILRDAEQ 180
  181 VQLRSFSTSM HKIDCQVAYR VNP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] PSI-BLAST 70.39794 The Mad2 spindle checkpoint protein possesses two distinct natively folded states

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.14424444268625 bayes_pls_golite062009
  • protein binding
    		•  0.856075580719879 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle