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Protein Overview: idh2

General Information:
Name(s) found: idh2 / SPBC902.05c [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • isocitrate dehydrogenase (NAD+) subunit 2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 378 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: glutamate biosynthetic process [IMPLink to PubMed article]
    isocitrate metabolic process [IMPLink to PubMed article]
    tricarboxylic acid cycle [IMPLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    isocitrate dehydrogenase (NAD+) activity [IMPLink to PubMed article]
    RNA binding [IEA]
    NAD or NADH binding [IEA]
    manganese ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMLSTLRTA GSLRTFSRSA CYSFRFSSTK AAAGTYEGVK NANGNYTVTM IAGDGIGPEI  60
   61 AQSVERIFKA AKVPIEWERV KVYPILKNGT TTIPDDAKES VRKNKVALKG PLATPIGKGH 120
  121 VSMNLTLRRT FGLFANVRPC VSITGYKTPY DNVNTVLIRE NTEGEYSGIE HEVIPGVVQS 180
  181 IKLITRAASE RVIRYAFQYA RQTGKNNITV VHKATIMRMA DGLFLECAKE LAPEYPDIEL 240
  241 REEILDNACL KIVTDPVPYN NTVMVMPNLY GDIVSDMCAG LIGGLGLTPS GNIGNQASIF 300
  301 EAVHGTAPDI AGKGLANPTA LLLSSVMMLK HMNLNDYAKR IESAIFDTLA NNPDARTKDL 360
  361 GGKSNNVQYT DAIISKLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..378] PSI-BLAST 108.0 No description for 2d1cA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.53

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle