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Protein Overview: hcs1

General Information:
Name(s) found: hcs1 / SPAC4F8.14c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • 3-hydroxy-3-methylglutaryl-CoA synthase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 447 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    endoplasmic reticulum [ICLink to PubMed article]
    Biological Process: farnesyl diphosphate biosynthetic process, mevalonate pathway [IMPLink to PubMed article]
    acetyl-CoA metabolic process [IMPLink to PubMed article]
    ergosterol biosynthetic process [IMPLink to PubMed article]
    Molecular Function: hydroxymethylglutaryl-CoA synthase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDRKDIGI KGLVLYTPNQ YVEQAALEAH DGVSTGKYTI GLGLTKMAFV DDREDIYSFG  60
   61 LTALSQLIKR YQIDISKIGR LEVGTETIID KSKSVKSVLM QLFGDNHNVE GIDCVNACYG 120
  121 GVNALFNTID WIESSAWDGR DGIVVAGDIA LYAKGNARPT GGAGCVALLV GPNAPIVFEP 180
  181 GLRGTYMQHA YDFYKPDLTS EYPYVDGHFS LECYVKALDG AYANYNVRDV AKNGKSQGLG 240
  241 LDRFDYCIFH APTCKQVQKA YARLLYTDSA AEPSNPELEG VRELLSTLDA KKSLTDKALE 300
  301 KGLMAITKER FNKRVSPSVY APTNCGNMYT ASIFSCLTAL LSRVPADELK GKRVGAYSYG 360
  361 SGLAASFFSF VVKGDVSEIA KKTNLVNDLD NRHCLTPTQY EEAIELRHQA HLKKNFTPKG 420
  421 SIERLRSGTY YLTGIDDMFR RSYSVKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..447] PSI-BLAST 104.0 No description for 2p8uA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle