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Protein Overview: his5

General Information:
Name(s) found: his5 / SPBC21H7.07c [Sanger Pombe]
Description(s) found:
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  • gi|729719|sp|P40374.1|HIS7_SCHPO RecName: Full=Imidazoleglycerol-phosphate dehydratase; Short=IGPD [NCBI NR]
  • gi|476142|gb|AAA92791.1| imidazoleglycerol-phosphate dehydratase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|3116116|emb|CAA18867.1| imidazoleglycerol phosphate dehydratase [Schizosaccharomyces pombe] [NCBI NR]
  • pir||S55077 imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19112724|ref|NP_595932.1| imidazoleglycerol phosphate dehydratase [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • imidazoleglycerol phosphate dehydratase [Sanger Pombe]
  • Imidazoleglycerol-phosphate dehydratase OS=Schizosaccharomyces pombe GN=his5 PE=1 SV=1 [Swiss-Prot]
  • IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE; SIMILAR TO S. CEREVISIAE HIS3: P40374; [pompepVF.fasta]
  • IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE: P40374; [pompepV13]
  • Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) (IGPD) [pompep4896]
  • |his5||imidazoleglycerol-phosphate dehydratase (PMID 8159167) [pompepnew.fasta]
  • |his5||imidazoleglycerol-phosphate dehydratase (PMID 8159167)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • |his5||imidazoleglycerol-phosphate dehydratase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • imidazoleglycerol-phosphate dehydratase [Schizosaccharomyces pombe]gi|3116116|emb|CAA18867.1| his5 [Schizosaccharomyces pombe]gi|729719|sp|P40374|HIS7_SCHPO Imidazoleglycerol-phosphate dehydratase (IGPD)gi|476142|gb|AAA92791.1| imidazoleglycerol-phosph [nrdb_11152004_Chlamydomonas]
  • (P40374) Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) (IGPD) [pompep4896_normal_reversed]
  • |his5||imidazoleglycerol phosphate dehydratase|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPBC21H7.07c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • imidazoleglycerol-phosphate dehydratase [nr-271106-contam.fasta]
  • hypothetical protein SPBC21H7.07c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Imidazoleglycerol-phosphate dehydratase (IGPD) [nr-271106-contam.fasta]
  • |his5||imidazoleglycerol-phosphate dehydratase His5|Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Imidazoleglycerol-phosphate dehydratase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=his5 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 216 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: histidine biosynthetic process [TASLink to PubMed article]
    Molecular Function: imidazoleglycerol-phosphate dehydratase activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRAFVERNT NETKISVAIA LDKAPLPEES NFIDELITSK HANQKGEQVI QVDTGIGFLD  60
   61 HMYHALAKHA GWSLRLYSRG DLIIDDHHTA EDTAIALGIA FKQAMGNFAG VKRFGHAYCP 120
  121 LDEALSRSVV DLSGRPYAVI DLGLKREKVG ELSCEMIPHL LYSFSVAAGI TLHVTCLYGS 180
  181 NDHHRAESAF KSLAVAMRAA TSLTGSSEVP STKGVL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..216] PSI-BLAST 81.0 Crystal structure of Imidazole Glycerol Phosphate Dehydratase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • imidazoleglycerol-phosphate dehydratase activity
    		•  1.6337728630325 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.369771518688522 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.325699575011026 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.212099606954236 bayes_pls_golite062009
  • structural molecule activity
    		•  2.19428886088058E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle