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Protein Overview: sup45

General Information:
Name(s) found: sup45 / SPAC1834.01 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • translation release factor eRF1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 433 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article][ISSLink to PubMed article]
    translation release factor complex [IPI]
    Biological Process: positive regulation of translational termination [ICLink to PubMed article]
    translational termination [IPILink to PubMed article]
    Molecular Function: translation release factor activity, codon specific [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETAEKAIE IWKIRRLVKQ LINCHGNGTS MITLIIPPGE QISRYSNMLA EEYGTASNIK  60
   61 SRVNRLSVLS AITSTRERLK LYNKVPDNGL VIYCGEVIME GNKTRKLNID FEPFKPINTS 120
  121 QYLCDNKFHT EALAELLESD QRFGFIVMDG HQTLYGVVSG SAREVLQRFT VDLPKKHGRG 180
  181 GQSALRFARL RDEKRHNYVR KVAEGAVQHF ITDDKPNVAG IVLAGSADFK TELGQSDLFD 240
  241 QRLQSRIIKT VDVSYGGDAG FNQAIELAAD TLSNVKYVQE KKLIQRFFDE ISLDSGKYCF 300
  301 GVVDTMNALQ EGAVETLLCF ADLDMIRYEF KNSEGNPVIT YMTKEQEEKD STNSFLLDKD 360
  361 TGAEMELVSS MLLSEWLAEH YKDYGANLEF VSDRSQEGMQ FVKGFGGIGA VMRYQLDLSM 420
  421 LDPESDEFYS DSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..433] PSI-BLAST 170.0 Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1; C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1; N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation release factor activity
    		•  11.5102558694213 bayes_pls_golite062009
  • translation termination factor activity
    		•  11.4768548464911 bayes_pls_golite062009
  • translation release factor activity, codon specific
    		•  7.66455753522311 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.97154934968642 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.70960972397471 bayes_pls_golite062009
  • structural molecule activity
    		•  2.64319832043379 bayes_pls_golite062009
  • binding
    		•  2.24516466558786 bayes_pls_golite062009
  • translation regulator activity
    		•  1.83257472130927 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.81472167858216 bayes_pls_golite062009
  • RNA binding
    		•  1.59103459949328 bayes_pls_golite062009
  • mRNA binding
    		•  0.607146672130391 bayes_pls_golite062009
  • protein binding
    		•  0.381324299701367 bayes_pls_golite062009
  • catalytic activity
    		•  0.264002643439785 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.62

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle