Protein Overview: tef5

General Information:
Name(s) found:	tef5 / SPCC1450.04 [Sanger Pombe]
Description(s) found: Found 19 descriptions. SHOW ALL	translation elongation factor EF-1 beta subunit [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	214 amino acids
Gene Ontology:
Cellular Component:	cytosol [IDA] eukaryotic translation elongation factor 1 complex [ISS]
Biological Process:	translational elongation [ISS] positive regulation of translational elongation [IC]
Molecular Function:	translation elongation factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFSDLTSDA GLKQLNDFLL DKSFIEGYEP SQADAVVFKA VGVAPDTAKY PNGARWYKQI  60
   61 ATYDLATLPG TAKEVSAYGP EGAAAAEEDE IDLFGSDEEE DPEAERIKAE RVAEYNKKKA 120
  121 AKPKAVHKSL VTLDVKPWDD ETPMDELEKA VRSIQMDGLV WGLSKLVPVG FGVNKFQINL 180
  181 VVEDDKVSLE ALQEELEGFE DYVQSTDIAA MSKL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	dam1	No Comments	Liu X, et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..80]	PSI-BLAST	11.69897	Class delta GST
2	View Details	[81..214]	PSI-BLAST	38.09691	SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
binding	1.25677962636026	bayes_pls_golite062009
transferase activity	1.05573069897577	bayes_pls_golite062009
catalytic activity	0.963623964325467	bayes_pls_golite062009
protein binding	0.509172505892898	bayes_pls_golite062009
nucleic acid binding	0.46030380837916	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	0.44372379417457	bayes_pls_golite062009
transcription regulator activity	0.385619646192102	bayes_pls_golite062009
RNA binding	0.382017633056715	bayes_pls_golite062009
glutathione transferase activity	0.20688408808374	bayes_pls_golite062009
receptor binding	0.195270520302129	bayes_pls_golite062009
DNA binding	0.175092771820973	bayes_pls_golite062009

2

Term	Confidence	Notes
translation elongation factor activity	12.3173391557088	bayes_pls_golite062009
translation factor activity, nucleic acid binding	7.81664120156021	bayes_pls_golite062009
translation regulator activity	7.77673515271111	bayes_pls_golite062009
binding	2.63855036019658	bayes_pls_golite062009
nucleic acid binding	2.61354904861592	bayes_pls_golite062009
actin binding	1.90340345597574	bayes_pls_golite062009
cytoskeletal protein binding	1.63487486759233	bayes_pls_golite062009
signal transducer activity	0.663610041920356	bayes_pls_golite062009
molecular transducer activity	0.663610041920356	bayes_pls_golite062009
protein binding	0.590516949627746	bayes_pls_golite062009
actin monomer binding	0.2298282502586	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle